Overview
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Uses & Benefits
Treatment of hypertension (high blood pressure), angina pectoris (chest pain), control of heart rate in certain tachyarrhythmias; may be used post-myocardial infarction as per physician advice.
How It Works
Atenolol is a cardioselective beta-1 adrenergic blocker. It reduces heart rate, cardiac contractility and cardiac output, and suppresses renin release, thereby lowering blood pressure and myocardial oxygen demand.
Directions for Use
Take orally as advised by the doctor, usually once daily at the same time each day, with or without food. Swallow with water; do not stop suddenly without medical advice. Dose adjustments may be needed in kidney disease and the elderly.
Side Effects
Bradycardia, dizziness, fatigue, cold hands/feet, low blood pressure, nausea, sleep disturbances
Warnings & Precautions
Do not stop abruptly (may worsen angina/trigger heart attack). Use with caution in asthma/COPD (can cause bronchospasm), diabetes (may mask hypoglycaemia symptoms), peripheral vascular disease, thyroid disorders, and depression. Contraindicated/avoid in severe bradycardia, heart block (2nd/3rd degree), cardiogenic shock, and uncontrolled heart failure unless directed by a cardiologist. Inform doctor before surgery/anaesthesia. Dose reduction may be required in renal impairment.
Drug Interactions
Other antihypertensives (additive hypotension), verapamil/diltiazem (risk of severe bradycardia/heart block), digoxin (bradycardia), clonidine (rebound hypertension if stopped improperly), NSAIDs (may reduce antihypertensive effect), insulin/oral antidiabetics (masked hypoglycaemia), beta-agonist bronchodilators (reduced effect), amiodarone/antiarrhythmics (conduction disturbances)