Drug | Tablet

Prevention (prophylaxis) of angina pectoris (chest pain) due to coronary artery disease; chronic stable angina

Nitroglycerin is converted to nitric oxide in vascular smooth muscle, causing relaxation. It predominantly dilates veins, reducing preload and myocardial oxygen demand, and also dilates coronary arteries to improve blood flow to the heart.

Oral tablet (modified/controlled release). Take exactly as prescribed, usually 1–2 times daily. Swallow whole with water; do not crush or chew. Can be taken with or without food. Maintain a nitrate-free interval (as advised) to reduce tolerance. Not for acute angina relief unless specifically advised by a doctor.

Headache, dizziness, flushing, lightheadedness, nausea, weakness, low blood pressure, palpitations

Schedule H: use only on prescription. May cause significant hypotension and dizziness—avoid driving/operating machinery if affected. Use with caution in low blood pressure, dehydration, severe anemia, recent heart attack, hypertrophic obstructive cardiomyopathy, aortic stenosis, increased intracranial pressure or history of stroke. Do not stop suddenly without medical advice. Seek urgent care for severe chest pain, fainting, or allergic reaction.

Contraindicated with PDE5 inhibitors (sildenafil, tadalafil, vardenafil) and riociguat due to severe hypotension. Additive BP lowering with other antihypertensives, diuretics, alcohol, tricyclic antidepressants, antipsychotics. Ergot alkaloids (e.g., ergotamine) may reduce antianginal effect and increase BP/ischemia risk.

Store at room temperature (below 25°C), protected from light and moisture. Keep in original strip/container and out of reach of children.

Nitrocontin 6.4 Tablet, Nitroglyn CR 2.6 Tablet, Angised SR 2.6 Tablet, Nitro SR 2.6 Tablet, Sustac 2.6 Tablet