Rx
CIPLA LIMITED
Valparin Chrono 200 Tablet
Drug | Tablet
Prescription RequiredIn stock
Price
₹149
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Delivery
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Product Highlights
Overview
Drug | Tablet
Uses & Benefits
Epilepsy (partial and generalized seizures), Bipolar disorder (acute mania and maintenance, as prescribed), Migraine prophylaxis (prevention)
How It Works
Valproate increases the level of the inhibitory neurotransmitter GABA in the brain and reduces abnormal neuronal firing. It also modulates voltage-gated sodium and calcium channels, helping stabilize electrical activity and prevent seizures/mood swings.
Directions for Use
Swallow tablet whole with water; do not crush/chew as it is prolonged-release. Take at the same time each day, preferably with food to reduce stomach upset. Dose and schedule are as prescribed; do not stop suddenly without medical advice.
Side Effects
Nausea, vomiting, abdominal pain, indigestion, diarrhea, increased appetite, weight gain, tremor, dizziness, drowsiness, hair loss, headache, elevated liver enzymes, thrombocytopenia
Warnings & Precautions
Prescription medicine. Risk of severe liver injury (especially in young children and in the first 6 months), pancreatitis, and hyperammonemic encephalopathy—seek urgent care for severe abdominal pain, persistent vomiting, jaundice, unusual drowsiness/confusion. Teratogenic: high risk of major birth defects and neurodevelopmental disorders; avoid in pregnancy unless no alternative—effective contraception required for women of childbearing potential. Monitor liver function, blood counts, and valproate levels as advised. Use caution in liver disease, bleeding disorders, mitochondrial disorders (e.g., POLG mutations), and in elderly (sedation/falls). Do not discontinue abruptly (seizure risk).
Drug Interactions
Carbamazepine, phenytoin, phenobarbital, lamotrigine (increased risk of serious rash—dose adjustment needed), topiramate (hyperammonemia), clobazam, benzodiazepines and other CNS depressants, aspirin/salicylates and anticoagulants/antiplatelets (bleeding risk), rifampicin, erythromycin, cimetidine, zidovudine, meropenem/imipenem (carbapenems reduce valproate levels markedly—avoid), alcohol
Storage Instructions
Store below 25°C, protect from moisture and light, keep in original strip/container and out of reach of children.
Substitutes
Valparin Chrono 200 Tablet (other pack), Valparin 200 Tablet, Encorate Chrono 200 Tablet, Divalproex ER 250 Tablet (equivalent strength differs—doctor to match dose), Valprol CR 200 Tablet
Frequently Asked Questions
What is this medicine used for?
Epilepsy (partial and generalized seizures), Bipolar disorder (acute mania and maintenance, as prescribed), Migraine prophylaxis (prevention)
What are the side effects?
Nausea, vomiting, abdominal pain, indigestion, diarrhea, increased appetite, weight gain, tremor, dizziness, drowsiness, hair loss, headache, elevated liver enzymes, thrombocytopenia
How does this medicine work?
Valproate increases the level of the inhibitory neurotransmitter GABA in the brain and reduces abnormal neuronal firing. It also modulates voltage-gated sodium and calcium channels, helping stabilize electrical activity and prevent seizures/mood swings.
How should I use this medicine?
Swallow tablet whole with water; do not crush/chew as it is prolonged-release. Take at the same time each day, preferably with food to reduce stomach upset. Dose and schedule are as prescribed; do not stop suddenly without medical advice.
How should I store this medicine?
Store below 25°C, protect from moisture and light, keep in original strip/container and out of reach of children.
Do I need a prescription for this product?
Yes, this product requires a valid prescription (Rx). Upload it during checkout when prompted.
Can prices or availability change?
Yes. Prices and availability can change based on inventory and serviceability. The latest details are shown at checkout.
How do I place an order?
Select a variant, add to cart, enter delivery address, upload prescription if required, and pay securely.
Manufacturer & Brand
Brand:CIPLA LIMITED
Manufacturer:CIPLA LIMITED
HSN Code:30049081
Alternatives
Alternatives are suggested by pharmacists after reviewing your order and prescription.
Disclaimer: Product information is for awareness only and does not replace medical advice. For Rx medicines, a valid prescription is required. Consult your doctor or pharmacist for personalized guidance.
Sources: Manufacturer labeling/pack insert, established medical literature (neurology/psychiatry pharmacology), regulatory safety communications (e.g., pregnancy risk warnings)
Availability depends on stock and serviceability.