Abhayrab Pf

Composition of Abhayrab Pf

Abhayrab Pf contains Purified Rabies Vaccine (PVRV), cell culture vaccine, lyophilized powder for injection (strength per vial: ). It belongs to the Inactivated viral vaccine (rabies vaccine) class of medicines.

Uses of Abhayrab Pf

• Pre-exposure and post-exposure prophylaxis against rabies following animal bites/scratches or other suspected rabies exposure
• as per national guidelines.

Key benefits

• Prevents rabies after suspected exposure
• Used for pre-exposure rabies protection in high-risk individuals
• Induces protective rabies neutralizing antibodies
• Helps prevent a uniformly fatal infection when given on time

How Abhayrab Pf works

It is an inactivated (killed) rabies virus vaccine that stimulates the immune system to produce rabies virus neutralizing antibodies. These antibodies help prevent rabies infection when given before exposure or promptly after exposure along with appropriate wound care (and rabies immunoglobulin when indicated).

How to take Abhayrab Pf

For intramuscular (IM) use only as directed by a physician. Reconstitute the lyophilized vaccine with the supplied diluent and use immediately; do not freeze after reconstitution. Administer in the deltoid muscle (anterolateral thigh in small children); avoid gluteal region. Follow recommended pre-exposure or post-exposure schedule as per national/WHO guidelines; for severe exposures, give rabies immunoglobulin in addition to vaccine.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take the missed dose of Abhayrab Pf as soon as you remember. If it is almost time for the next dose, skip the missed one and carry on with the usual schedule. Do not take two doses together to make up for a missed dose.

If you take too much

Taking more Abhayrab Pf than prescribed can be harmful. If you suspect an overdose, contact a doctor or go to the nearest emergency department at once, and carry the pack or strip with you. In India the emergency number is 112.

Side effects of Abhayrab Pf

Most side effects of Abhayrab Pf are mild and settle as the body adjusts. Reported side effects include:

• Injection site pain
• redness
• swelling
• fever
• headache
• dizziness
• nausea
• vomiting
• abdominal pain
• muscle aches
• fatigue
• rash
• itching

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Abhayrab Pf

Warnings and precautions

Rabies is fatal—do not delay vaccination after exposure. Proper wound washing and medical evaluation are essential; rabies immunoglobulin is required for category III exposures (as per guidelines). Do not administer intravenously. Use with caution in persons with acute severe febrile illness (vaccination may be postponed if appropriate). History of severe allergic reaction (anaphylaxis) to a previous dose or vaccine components is a contraindication; ensure emergency treatment is available. Immunocompromised patients may have reduced response and may need antibody testing/extra doses per guidelines.

Interactions with other medicines

Immunosuppressants (e.g., high-dose corticosteroids, chemotherapy, biologics) may reduce vaccine response; chloroquine may reduce response to intradermal rabies vaccination; concomitant administration with rabies immunoglobulin is permitted for post-exposure prophylaxis but should be given at different sites and not mixed in the same syringe.

How to store Abhayrab Pf

Store refrigerated at 2–8°C. Do not freeze. Protect from light. After reconstitution, use immediately and discard any unused portion.

Manufacturer and class

Manufacturer:

HUMAN BIOLOGICALS LIMITED

Therapeutic class:

Vaccine / Immunological

Drug class:

Inactivated viral vaccine (rabies vaccine)