Drug | Tablet

High cholesterol (hypercholesterolemia), mixed dyslipidemia, high triglycerides; prevention of cardiovascular events (heart attack, stroke) in high-risk patients

Atorvastatin is an HMG-CoA reductase inhibitor (statin). It reduces cholesterol synthesis in the liver, lowering LDL and triglycerides and modestly increasing HDL, thereby reducing atherosclerotic risk.

Take as directed by a doctor, usually once daily at the same time each day, with or without food. Swallow whole with water; continue diet/exercise advised for cholesterol control.

Headache, nausea, diarrhea, abdominal pain, constipation, indigestion, muscle pain, weakness, joint pain, elevated liver enzymes

Contraindicated in active liver disease or unexplained persistent elevation of liver enzymes. Risk of muscle problems (myopathy/rhabdomyolysis) increases with higher doses and interacting drugs—seek medical help for unexplained muscle pain, tenderness, weakness, fever or dark urine. Monitor liver function if advised. Use caution in kidney disease, hypothyroidism, heavy alcohol use, and in the elderly. Avoid grapefruit juice in large amounts.

Strong CYP3A4 inhibitors (clarithromycin/erythromycin, ketoconazole/itraconazole, HIV protease inhibitors, cobicistat), cyclosporine, fibrates (especially gemfibrozil), niacin, colchicine, amiodarone, verapamil/diltiazem, warfarin (INR monitoring), digoxin, grapefruit juice

Store below 25°C in a cool, dry place away from moisture and direct light. Keep out of reach of children.

Atorsave 10 Tablet, Avas 10 Tablet, Aztor 10 Tablet, Aztor 20 Tablet, Atorva 10 Tablet