Peribrim Np Tablet

Peribrim Np Tablet contains METHYLCOBALAMIN-1500MCG+NORTRIPTYLINE-10MG+PREGABALIN-75MG and is used for this medicine is used. Prescription required.

This medicine is used in the treatment of vitamin b deficiency, nerve pain and tingling, anaemia, tiredness due to deficiency, depression, anxiety, obsessive compulsive disorder, nerve pain, migraine prevention, diabetic neuropathy, pain after shingles, fibromyalgia and epilepsy.

This medicine combines 3 active ingredients: Methylcobalamin, Nortriptyline and Pregabalin. Methylcobalamin replaces a B vitamin your body needs to make red blood cells, to keep nerves healthy and to release energy from food. Nortriptyline restores the balance of the chemical messengers in the brain that regulate mood, sleep and the way pain is felt. Pregabalin calms the over-active nerve signals that cause burning, shooting and tingling pain.

Swallow the tablet whole with a glass of water. Do not chew, crush or break it unless your doctor has told you to. Take it with or after food. Taking it at about the same time each day helps you remember. Follow the dose and the duration written on your prescription.

Nausea, Stomach upset, Harmless bright yellow urine, Loose motions, Dry mouth, Drowsiness or difficulty sleeping, Headache, Weight change, Reduced sexual desire, Constipation, Drowsiness, Dizziness, Swelling of the ankles and feet, Weight gain, Blurred vision, Unsteadiness

Tingling, numbness or burning in the hands and feet should be assessed by a doctor rather than self-treated — a supplement does not address the cause. Folic acid can mask a vitamin B12 deficiency while nerve damage continues, so B12 should be checked before taking folic acid long term. Bright yellow urine after a B-complex dose is expected and harmless. These medicines take two to four weeks to begin working, and longer for the full effect. Stopping at two weeks because nothing has changed is the commonest mistake. Never stop suddenly. Abrupt withdrawal causes dizziness, electric-shock sensations, irritability and flu-like symptoms — your doctor will reduce the dose gradually. Tell your doctor or go to hospital immediately if thoughts of harming yourself appear or worsen, particularly in the first weeks or after a dose change, and especially in anyone under twenty-five. Seek urgent care for agitation with fever, shivering, a racing heart, muscle twitching or confusion, particularly if more than one medicine affecting serotonin is being taken. Side effects are usually worst in the first fortnight and then settle. This medicine causes drowsiness and unsteadiness, particularly when you start it or the dose goes up. Do not drive or operate machinery until you know how it affects you. Never stop it suddenly. Stopping abruptly can cause anxiety, sleeplessness, sweating and, in people taking it for epilepsy, fits. Your doctor will taper it. Tell your doctor about any change in mood or any thoughts of harming yourself. The dose is usually built up slowly from a low starting point — follow the schedule your doctor gave you rather than jumping to the full dose. Pregabalin comes under Schedule H1 from 16 November 2026 and will then need a prescription and a pharmacy register entry.

Long-term metformin, acid-reducing medicines and some anti-epileptics lower B12 or folate levels. Tell your doctor if you take levodopa, as vitamin B6 can reduce its effect. Tramadol, triptans for migraine, linezolid, St John's wort and other antidepressants can together raise serotonin dangerously. Anti-inflammatory painkillers and blood thinners increase the bleeding risk when combined with this group. Opioid painkillers, alcohol, sleeping tablets and antihistamines all add to the drowsiness, and the combination with opioids can dangerously slow breathing. Antacids reduce the absorption of gabapentin — separate them by a couple of hours.

Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.