Total prostate-specific antigen
- Blood
- 24–48 hours
- Home pickup
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Prostate tests compared
Total PSA is the standard prostate screen. The free-PSA ratio helps decide next steps when PSA is mildly raised.
The bottom line
For prostate screening in men — typically from around age 50, or 45 with family history — total PSA is the standard first test. The free-PSA ratio is a follow-up, not a starting point: when total PSA is mildly raised, the ratio helps distinguish benign enlargement from something needing further work-up, and can spare an unnecessary biopsy. Start with total PSA; add the free ratio only if the total is borderline. Always interpret PSA with a doctor.
It's a routine prostate screen.
See price & bookPick Free : Total PSAYour total PSA is mildly raised and you need to decide next steps.
See price & bookPSA is a protein made by the prostate, and a raised total PSA can reflect benign enlargement, inflammation or, less commonly, cancer — so on its own it can't tell those apart. It remains the standard first-line screening test.
The free-PSA ratio compares the unbound fraction to the total. When total PSA sits in a grey zone, a higher free ratio points more toward benign causes and a lower ratio toward needing further assessment — a useful way to avoid over-investigating. It only makes sense as a second step once total PSA is known.
| Total PSA Standard prostate screen | Free : Total PSA Interprets a borderline PSA | |
|---|---|---|
| Use as first screen | Yes | No — follow-up |
| Helps avoid unnecessary biopsy | Limited | Yes |
| Fasting needed | No | No |
| Best sequence | Book first | Add if total is borderline |
Total prostate-specific antigen
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Heads up: Raised by benign enlargement and inflammation too
Free-to-total PSA ratio
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Heads up: Only meaningful once total PSA is known
Or get everything in one panel
107-parameter screening — PSA, testosterone, cardiac risk & complete checkup
Free home collection
A phlebotomist visits at your chosen time.
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Reports to your dashboard
Digital reports, usually within hours.
A registered doctor reviews your symptoms and history, tells you exactly which test you need, and interprets the results with you.
This page is general information to help you choose a test, not a diagnosis or medical advice. Lab results should be interpreted by a doctor alongside your symptoms and history.