
Dhkzcol Wet Collagen Sheet
Bioregen Technologies - 5 X5 Cm
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Demineralized Bone Matrix (DBM), 2 cc (sterile)
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Dhkzcol-Dbm 2Cc Sterile Bone Matrix is used for bone graft substitute/osteoconductive-osteoinductive matrix used to fill bony voids or defects in orthopaedic, trauma, spinal and dental/maxillofacial procedures (e.g., fracture non-union, fusion support, cyst/defect filling) as per surgeon discretion.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Dhkzcol-Dbm 2Cc Sterile Bone Matrix contains Demineralized Bone Matrix (DBM), 2 cc (sterile). It belongs to the Demineralized bone matrix (DBM) allograft (orthobiologic) class of medicines.
DBM is processed allograft bone with minerals removed, preserving collagen matrix and native growth factors. It provides a scaffold for new bone growth (osteoconduction) and can stimulate bone formation (osteoinduction), aiding defect healing when implanted in a prepared bony site.
For surgical use only. Use aseptic technique; prepare/shape and place DBM into the bone defect as directed by the operating surgeon. Do not use if pack is damaged or product is contaminated; single-use only and discard any unused material.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
Take the missed dose of Dhkzcol-Dbm 2Cc Sterile Bone Matrix as soon as you remember. If it is almost time for the next dose, skip the missed one and carry on with the usual schedule. Do not take two doses together to make up for a missed dose.
Taking more Dhkzcol-Dbm 2Cc Sterile Bone Matrix than prescribed can be harmful. If you suspect an overdose, contact a doctor or go to the nearest emergency department at once, and carry the pack or strip with you. In India the emergency number is 112.
Most side effects of Dhkzcol-Dbm 2Cc Sterile Bone Matrix are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Consult doctor |
|---|---|
| Alcohol | No known interaction |
| Habit forming | No |
Rx/Surgical implant—use only by qualified healthcare professionals. Risk of infection and disease transmission with human tissue-derived grafts; follow institutional protocols. Do not use if sterile barrier is compromised or beyond expiry. Not for intravascular use; avoid placement into infected/necrotic sites unless appropriately managed. Use caution in patients with active infection, poor vascularity, metabolic bone disorders, immunosuppression, or compromised healing. Adverse events may require removal or revision surgery.
No specific drug-drug interactions known; concomitant factors that impair bone healing (e.g., chronic corticosteroids, chemotherapy, high-dose NSAIDs, smoking) may reduce graft incorporation as per clinical judgment.
Store as per label instructions; generally keep in original sterile pack, protected from light and moisture. Do not use if packaging is damaged. Maintain recommended storage temperature specified on the pack/IFU.

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The information on Dhkzcol-Dbm 2Cc Sterile Bone Matrix is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.