Distributor inventory

Bone graft substitute/osteoconductive-osteoinductive matrix used to fill bony voids or defects in orthopaedic, trauma, spinal and dental/maxillofacial procedures (e.g., fracture non-union, fusion support, cyst/defect filling) as per surgeon discretion.

DBM is processed allograft bone with minerals removed, preserving collagen matrix and native growth factors. It provides a scaffold for new bone growth (osteoconduction) and can stimulate bone formation (osteoinduction), aiding defect healing when implanted in a prepared bony site.

For surgical use only. Use aseptic technique; prepare/shape and place DBM into the bone defect as directed by the operating surgeon. Do not use if pack is damaged or product is contaminated; single-use only and discard any unused material.

Local pain, swelling, inflammation, infection, wound complications, graft failure/non-union, immune reaction, hematoma, ectopic/heterotopic bone formation

Rx/Surgical implant—use only by qualified healthcare professionals. Risk of infection and disease transmission with human tissue-derived grafts; follow institutional protocols. Do not use if sterile barrier is compromised or beyond expiry. Not for intravascular use; avoid placement into infected/necrotic sites unless appropriately managed. Use caution in patients with active infection, poor vascularity, metabolic bone disorders, immunosuppression, or compromised healing. Adverse events may require removal or revision surgery.

No specific drug-drug interactions known; concomitant factors that impair bone healing (e.g., chronic corticosteroids, chemotherapy, high-dose NSAIDs, smoking) may reduce graft incorporation as per clinical judgment.

Store as per label instructions; generally keep in original sterile pack, protected from light and moisture. Do not use if packaging is damaged. Maintain recommended storage temperature specified on the pack/IFU.

Grafton DBM (Medtronic), Opteform DBM, AlloMatrix DBM Putty, Osteoinductive DBM Putty (various brands), CollaGraft/other bone graft substitutes (as available)