Glucomust M 5/500 Tablet — Uses, Dosage & Benefits

Glipizide 5mg + Metformin 500mg

Glipizide closes pancreatic beta‑cell ATP‑sensitive K+ (KATP; SUR1) channels, depolarising the cell and increasing Ca2+ influx to trigger insulin release. Metformin activates AMP‑activated protein kinase (AMPK), suppressing hepatic gluconeogenesis and improving peripheral insulin sensitivity while decreasing intestinal glucose absorption.

Glucomust M 5/500 Tablet is usually taken 1 tablet once daily with breakfast or the main meal initially; if prescribed twice daily, take with breakfast and dinner to reduce gastrointestinal upset and hypoglycaemia. Swallow whole with water; do not skip meals after taking the 5mg glipizide/500mg metformin combination.

Always follow your doctor's prescription. Do not self-medicate.