Prescription requiredCorticosteroid (Anti-inflammatory/Immunosuppressant)

Medrol 4 Tablet — Side Effects & Warnings

Known side effects of Medrol 4 Tablet include Indigestion, nausea, increased appetite, weight gain, mood changes, insomnia, headache, increased blood sugar, fluid retention, increased blood pressure. Not everyone experiences these side effects.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated June 2026

Common Side Effects

Indigestion
nausea
increased appetite
weight gain
mood changes
insomnia
headache
increased blood sugar
fluid retention
increased blood pressure

This is not an exhaustive list. Consult your doctor if you notice any unusual symptoms.

Important Warnings

Schedule H: use only on prescription. Do not stop abruptly—risk of adrenal suppression; tapering may be required. Can increase risk of infections and mask signs of infection; avoid close contact with people having contagious infections and consult doctor if fever occurs. Use caution in diabetes, hypertension, peptic ulcer disease, osteoporosis, glaucoma/cataract, thyroid disorders, liver disease, and in elderly. Avoid live vaccines during high-dose/systemic therapy. Long-term use may cause Cushingoid features, bone loss, muscle weakness, and growth suppression in children; regular monitoring may be needed.

Drug Interactions

Medrol 4 Tablet may interact with the following:

NSAIDs (increased GI ulcer/bleeding risk)
anticoagulants like warfarin (altered INR)
antidiabetics/insulin (reduced glucose control)
diuretics like furosemide (hypokalemia)
digoxin (arrhythmia risk with low potassium)
CYP3A4 inducers like rifampicin/phenytoin/carbamazepine (reduced effect)
CYP3A4 inhibitors like ketoconazole/ritonavir (increased steroid effects)
live vaccines (infection risk)

Always tell your doctor about all medicines you are taking, including over-the-counter drugs and supplements.

Pregnancy Safety

Use with caution / Consult doctor (use only if clearly needed; lowest effective dose)

Alcohol Interaction

Use with caution (may increase stomach irritation/ulcer risk)

Habit Forming

Storage

Store below 25°C in a dry place, protected from moisture and light. Keep out of reach of children.

Medrol 4 Tablet — Safety Summary

Composition: Methylprednisolone (4mg)
Prescription: Required (Rx)
Pregnancy: Use with caution / Consult doctor (use only if clearly needed; lowest effective dose)
Alcohol: Use with caution (may increase stomach irritation/ulcer risk)
Habit forming: No

Medrol 4 Tablet — Safety FAQs

What should I do if I experience side effects?

Mild side effects often resolve on their own. If side effects are severe or persistent, stop the medicine and consult your doctor immediately.

Are all listed side effects common?

No. Some side effects are common while others are rare. Not everyone experiences side effects. Consult your doctor if you are concerned.

Can I take this medicine with other drugs?

Some medicines interact with each other. Always inform your doctor about all medicines you are currently taking.

When should I seek emergency help?

Seek immediate medical attention if you experience severe allergic reactions (difficulty breathing, swelling of face/throat), chest pain, or any life-threatening symptoms.

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Safety disclaimer

This information is for educational purposes only and is not a substitute for professional medical advice. If you experience severe side effects, seek medical attention immediately.

Medrol 4 Tablet — Side Effects & Warnings

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated June 2026