Drug | Injection
Ofloxacin 200 mg/100 mL intravenous infusion (2 mg/mL)
Treatment of susceptible bacterial infections such as urinary tract infections, respiratory tract infections, skin and soft tissue infections, gastrointestinal infections (including enteric fever/typhoid where appropriate) and other systemic infections when IV therapy is required
Ofloxacin is a fluoroquinolone antibiotic. It inhibits bacterial DNA gyrase (topoisomerase II) and topoisomerase IV, blocking DNA replication and repair, leading to bacterial cell death.
For intravenous infusion only; administer by slow IV infusion as prescribed by the physician. Dose and duration depend on infection type and kidney function. Do not give as IV bolus or intramuscular injection; ensure compatibility with IV fluids and avoid mixing with incompatible medicines in the same line.
Common side effects of Oflotas Infusion may include:
Use only for bacterial infections; inappropriate use increases resistance. Fluoroquinolones may cause tendonitis/tendon rupture, peripheral neuropathy, CNS effects (seizures, confusion), QT prolongation/arrhythmias, severe hypersensitivity reactions and Clostridioides difficile-associated diarrhea—stop and seek care if symptoms occur. Use with caution in epilepsy/CNS disorders, myasthenia gravis, heart rhythm disorders, and in elderly. Adjust dose in renal impairment. Avoid unnecessary sun/UV exposure (photosensitivity).
