Oflotas Infusion

Drug | Injection

Treatment of susceptible bacterial infections such as urinary tract infections, respiratory tract infections, skin and soft tissue infections, gastrointestinal infections (including enteric fever/typhoid where appropriate) and other systemic infections when IV therapy is required

Ofloxacin is a fluoroquinolone antibiotic. It inhibits bacterial DNA gyrase (topoisomerase II) and topoisomerase IV, blocking DNA replication and repair, leading to bacterial cell death.

For intravenous infusion only; administer by slow IV infusion as prescribed by the physician. Dose and duration depend on infection type and kidney function. Do not give as IV bolus or intramuscular injection; ensure compatibility with IV fluids and avoid mixing with incompatible medicines in the same line.

nausea, vomiting, diarrhea, abdominal pain, headache, dizziness, insomnia, rash, injection-site pain/phlebitis, elevated liver enzymes

Use only for bacterial infections; inappropriate use increases resistance. Fluoroquinolones may cause tendonitis/tendon rupture, peripheral neuropathy, CNS effects (seizures, confusion), QT prolongation/arrhythmias, severe hypersensitivity reactions and Clostridioides difficile-associated diarrhea—stop and seek care if symptoms occur. Use with caution in epilepsy/CNS disorders, myasthenia gravis, heart rhythm disorders, and in elderly. Adjust dose in renal impairment. Avoid unnecessary sun/UV exposure (photosensitivity).

Drugs that prolong QT (e.g., amiodarone, sotalol, macrolides, antipsychotics), corticosteroids (increased tendon rupture risk), antidiabetic agents/insulin (dysglycemia), warfarin (may increase INR/bleeding), NSAIDs (may increase CNS stimulation/seizure risk), probenecid/cimetidine (may reduce renal clearance)

Store below 25°C; protect from light. Do not freeze. Keep in original container; use only if solution is clear and container intact.

Zanocin IV Infusion, Oflox IV Infusion, Oflocin IV Infusion, Tarivid IV Infusion, Oflox-200 IV Infusion