Drug | Tablet
Tramadol hydrochloride 37.5 mg + Paracetamol (Acetaminophen) 325 mg
Moderate to moderately severe acute pain (e.g., musculoskeletal pain, dental pain, postoperative pain) when an opioid/non-opioid combination is appropriate
Paracetamol reduces pain by inhibiting prostaglandin synthesis in the central nervous system. Tramadol is an opioid analgesic that also inhibits reuptake of serotonin and norepinephrine, enhancing descending pain inhibition. The combination provides additive analgesia.
Oral tablet. Take exactly as prescribed. Common adult dosing is 1–2 tablets every 4–6 hours as needed for pain; swallow with water, with or without food. Do not exceed the prescribed dose or total daily paracetamol from all sources; use for the shortest duration needed.
Common side effects of Ultracet Tablet may include:
May cause drowsiness—avoid driving/operating machinery. Risk of dependence, misuse and withdrawal with tramadol. Do not use with other paracetamol-containing products; overdose can cause severe liver damage. Use caution in liver or kidney disease, elderly, head injury, respiratory disease/asthma, history of seizures, and in patients at risk of serotonin syndrome. Avoid in severe respiratory depression or acute alcohol/other CNS depressant intoxication. Seek urgent help for slow/shallow breathing, severe sleepiness, allergic reactions, or signs of liver injury (yellowing of skin/eyes, dark urine).
