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Prescription requiredMankind (pharma)PAIN ANALGESICS

Tramasure Plus Rf Tablet

Tramadol (37.5mg) + Paracetamol (325mg)

Available at our pharmacy counter

This medicine is dispensed in person against a valid prescription and is not sold online. Ask our pharmacist about availability, or speak to a registered doctor.

In-store reference price ₹83

Tramasure Plus Rf Tablet is used for moderate to severe pain.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026

Licensed pharmacyPharmacist-verified order

Key details

Salt: Tramadol (37.5mg) + Paracetamol (325mg)
Available variants: tablet 37.5mg + 325mg 10`S
Best price: ₹83 (₹8.28 per tablet)
MRP: ₹87
Prescription: Required
Manufacturer: MANKIND (PHARMA)

Ordering notes

This medicine is dispensed in person at a licensed pharmacy counter and is not delivered.
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Composition of Tramasure Plus Rf Tablet

Tramasure Plus Rf Tablet contains Tramadol (37.5mg) + Paracetamol (325mg). It belongs to the Opioid analgesic and Para-aminophenol derivative class of medicines.

Uses of Tramasure Plus Rf Tablet

Moderate to severe pain

Key benefits

  • In Moderate to severe pain Tramasure-Plus RF Tablet works by acting on the brain to alter pain perception and by blocking pain signals. This helps provide faster and more effective relief from intense pain. Timely pain control can improve mobility and support recovery. As a result
  • patients may experience greater comfort and improved ability to perform daily activities.

How Tramasure Plus Rf Tablet works

Tramasure-Plus RF Tablet is a combination of two medicines: Tramadol and Paracetamol which relieve severe pain. Tramadol is an opioid analgesic (pain reliever) which works by blocking the transmission of pain signals to the brain to lower pain perception. Paracetamol works by blocking the release of certain chemical messengers that cause pain.

How to take Tramasure Plus Rf Tablet

Take exactly as prescribed by your doctor.

Side effects of Tramasure Plus Rf Tablet

Most side effects of Tramasure Plus Rf are mild and settle as the body adjusts. Reported side effects include:

  • Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Tramasure Plus Rf Tablet

PregnancyPregnancy CONSULT YOUR DOCTOR
BreastfeedingBreast feeding SAFE IF PRESCRIBED
AlcoholAlcohol UNSAFE
DrivingDriving UNSAFE
KidneyKidney CAUTION
LiverLiver CAUTION
Habit formingYes

Warnings and precautions

Take it with or just after food, and for the shortest time that works. Stop and seek urgent care for black or tarry stools, vomiting blood, or severe stomach pain — this group can cause bleeding from the stomach. Long or high-dose use raises the risk of heart attack, stroke and kidney injury, particularly in older people and those already at risk. Avoid if you are dehydrated or have an illness with vomiting or loose motions — the kidneys are vulnerable then. Must be avoided in the last three months of pregnancy. This is an opioid painkiller. It can cause dependence, and should be taken only for the period your doctor has specified. Never combine it with alcohol, sleeping tablets or other sedatives — together they can dangerously slow your breathing. Do not stop a long course abruptly; your doctor will reduce it gradually. Tell your doctor if you have epilepsy or take an antidepressant — tramadol can lower the seizure threshold and can raise serotonin dangerously in combination. Never exceed the daily maximum printed on the pack. Paracetamol overdose damages the liver, and the damage can be silent for a day or two before it becomes serious. Check every other medicine you are taking. Paracetamol is in a very large number of cold, flu and pain combinations, and the doses add together. If you drink alcohol regularly, or have liver disease, ask your doctor what daily limit is safe for you. See a doctor if fever lasts more than three days, or pain more than five.

Do not take Tramasure Plus Rf if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with an active stomach ulcer, severe kidney or heart failure, or asthma triggered by aspirin or anti-inflammatory painkillers. Not in the third trimester of pregnancy. Not for people with severe liver disease, except under medical supervision.

Interactions with other medicines

Combining with a blood thinner or aspirin sharply raises the bleeding risk. Reduces the effect of blood pressure medicines and water tablets, and together with them can harm the kidneys. Never take two anti-inflammatory painkillers at the same time. Regular alcohol use increases the risk of liver injury. Tell your doctor if you are on warfarin — regular high-dose paracetamol can affect it.

How to store Tramasure Plus Rf Tablet

Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.

Expert advice for Tramasure Plus Rf Tablet

Consider taking Tramasure-Plus RF Tablet with milk or food to prevent stomach upset. Tramasure-Plus RF Tablet may cause drowsiness, dizziness, or slowed reaction time, particularly when you first start taking it. It is recommended to avoid driving or operating heavy machinery until you are certain how it affects you. Drink plenty of water and eat fiber-rich foods like fruits and vegetables to help prevent constipation, a common side effect of Tramasure-Plus RF Tablet. Do not drink alcohol while taking Tramasure-Plus RF Tablet. Alcohol combined with this medicine can cause extreme drowsiness or dangerously slow your breathing. During long-term treatment, your doctor may conduct regular blood tests to monitor your liver function. Inform your doctor if you have a history of heart disease, high blood pressure, liver disease, kidney disease, epilepsy, or any breathing problems before taking Tramasure-Plus RF Tablet. Do not stop taking Tramasure-Plus RF Tablet suddenly if you have been using it for more than a few days. Stopping it abruptly may lead to withdrawal symptoms such as anxiety, restlessness, sweating, insomnia, and gastrointestinal discomfort.

Manufacturer and class

Manufacturer:
MANKIND (PHARMA)
Therapeutic class:
PAIN ANALGESICS
Drug class:
Opioid analgesic and Para-aminophenol derivative

Substitutes for Tramasure Plus Rf Tablet

Medicines with the same active ingredient (Tramadol (37.5mg) + Paracetamol (325mg)). Ask your doctor or pharmacist before switching brands.

MedicinePackPricevs Tramasure Plus Rf Tablet
Ultra PlusICON PHARMA10`S₹11843% more
Tramand TabletCOGNYZON PHARMACEUTICALStablet · 10`S₹13361% more
Trabest TabletLUPIN LABtablet · 10`S₹13664% more
Ultrazac TabletZYDUS HEALTHCARE PHARMAtablet · 10`S₹14069% more
Tramef P Tablet15₹14170% more
UltramedPharmed Ltd15`S₹191130% more
Ultram TabletMICRO LABStablet · 15`S₹213157% more
Ifimol-T Tablet15'S₹229176% more
Ultracet TabletJohnson & Johnson Pvt Ltdtablet · 15 Tablet₹281239% more
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Tramasure Plus Rf Tablet FAQs

What is Tramasure Plus Rf Tablet used for?
Tramasure Plus Rf Tablet is commonly used for Moderate to severe pain. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Tramasure Plus Rf Tablet?
Tramasure Plus Rf Tablet contains Tramadol (37.5mg) + Paracetamol (325mg). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How does Tramasure Plus Rf Tablet work?
Tramasure-Plus RF Tablet is a combination of two medicines: Tramadol and Paracetamol which relieve severe pain.
Is Tramasure Plus Rf Tablet a prescription medicine?
Yes. Tramasure Plus Rf Tablet is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Tramasure Plus Rf Tablet?
The side effects reported most often with Tramasure Plus Rf are Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Tramasure Plus Rf Tablet be taken during pregnancy?
Pregnancy CONSULT YOUR DOCTOR Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Tramasure Plus Rf.
Can I drink alcohol while taking Tramasure Plus Rf Tablet?
Alcohol UNSAFE
Is Tramasure Plus Rf Tablet habit forming?
Yes Take Tramasure Plus Rf only as directed and for the duration your doctor advises.
How much does Tramasure Plus Rf Tablet cost on PingMeDoc Pharmacy?
Tramasure Plus Rf Tablet starts at ₹83 (MRP ₹87) on PingMeDoc Pharmacy. Available in tablet 37.5mg + 325mg 10`S. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Tramasure Plus Rf Tablet?
Tramasure Plus Rf Tablet is manufactured by MANKIND (PHARMA). PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Tramasure Plus Rf Tablet delivered?
Tramasure Plus Rf Tablet is a regulated medicine and is not delivered. It is dispensed in person at a licensed pharmacy counter against a valid prescription. Ask our pharmacist on WhatsApp about availability.

Tramasure Plus Rf Tablet, Quick facts

Salt
Tramadol (37.5mg) + Paracetamol (325mg)
Form
tablet
Best price
₹83 (₹8.28 per tablet)
MRP
₹87
Prescription
Required (Rx)
Schedule
Schedule H1
Brand
MANKIND (PHARMA)
Manufacturer
MANKIND (PHARMA)
Therapeutic class
PAIN ANALGESICS
Drug class
Opioid analgesic and Para-aminophenol derivative
Habit forming
Yes
Variants
tablet 37.5mg + 325mg 10`S
Delivery
Standard across India

References

The information on Tramasure Plus Rf Tablet is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.

  1. PingMeDoc clinical monograph library — compiled from Indian package inserts, the Indian Pharmacopoeia
  2. CDSCO schedules and standard pharmacology references. Reviewed for patient readability. This is general information, not a substitute for your doctor's advice.
  3. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  4. National List of Essential Medicines (NLEM) 2022, Government of India.
  5. Manufacturer's package insert / prescribing information for Tramasure Plus Rf Tablet.
  6. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.