Drug | Tablet

Prevention and treatment of blood clots (thromboembolism) such as deep vein thrombosis (DVT), pulmonary embolism (PE); prevention of stroke/systemic embolism in atrial fibrillation; prevention of clotting in patients with prosthetic heart valves and other high-risk conditions

Acenocoumarol is a vitamin K antagonist anticoagulant. It inhibits vitamin K–dependent clotting factors (II, VII, IX, X) in the liver, reducing the blood’s ability to form clots. Its effect is monitored using PT/INR.

Take exactly as prescribed by your doctor, usually once daily at the same time each day. Dose is individualized based on INR; do not change dose or stop without medical advice. Can be taken with or without food; keep dietary vitamin K intake consistent and attend regular INR testing.

Bleeding, easy bruising, nosebleeds, bleeding gums, blood in urine, black/tarry stools, nausea, vomiting, abdominal discomfort, diarrhea, rash, hair loss, dizziness

High risk of serious bleeding; seek urgent care for unusual bleeding, severe headache, weakness, vomiting blood, or black stools. Requires regular PT/INR monitoring. Use with caution in liver or kidney disease, uncontrolled hypertension, history of bleeding, peptic ulcer, recent surgery/trauma, alcohol misuse, and in elderly patients. Maintain consistent vitamin K intake; avoid sudden dietary changes. Inform healthcare providers before any procedure/dental work. Do not self-medicate with painkillers like NSAIDs without advice.

Other anticoagulants (heparin, DOACs), antiplatelets (aspirin, clopidogrel), NSAIDs (ibuprofen, diclofenac), many antibiotics (e.g., macrolides, fluoroquinolones, cotrimoxazole), antifungals (azole group), amiodarone, statins (some), antiepileptics (phenytoin, carbamazepine), thyroid hormones, SSRIs/SNRIs, corticosteroids, herbal products (St John’s wort, ginkgo, garlic) and vitamin K-containing supplements/foods

Store at room temperature (below 25°C), in a dry place away from moisture and direct light. Keep in original blister pack and out of reach of children.

Acitrom 1 Tablet, Acitrom 2 Tablet, Acitrom 3 Tablet