Do not use if you have untreated nasal infections. Prolonged or excessive use of decongestant-containing sprays may cause rebound congestion. Use with caution in hypertension, heart disease, hyperthyroidism, diabetes, glaucoma, prostate enlargement, or if taking antidepressants (MAO inhibitors). Seek medical advice if symptoms persist beyond a few days, you develop severe nosebleeds, or have visual changes.