Drug | Injection

Treatment and prevention of vitamin D deficiency, Rickets, Osteomalacia, Adjunct in osteoporosis and hypocalcaemia due to vitamin D deficiency

Cholecalciferol is converted in the liver and kidneys to active vitamin D (calcitriol). It increases intestinal absorption of calcium and phosphate and helps normalize bone mineralization and parathyroid hormone levels.

Administer only under medical supervision as an intramuscular injection. Dose and frequency are decided by the physician based on vitamin D levels and clinical condition; may be given with or without food as it is injectable.

Injection site pain, nausea, vomiting, constipation, loss of appetite, headache, weakness, increased thirst, increased urination

Risk of hypercalcaemia and vitamin D toxicity with excessive dosing—monitor serum calcium, phosphate and 25(OH)D especially with repeated high-dose use. Use with caution in kidney disease, history of kidney stones, hyperparathyroidism, sarcoidosis or other granulomatous disorders. Contraindicated in hypercalcaemia, hypervitaminosis D and hypersensitivity to vitamin D preparations.

Thiazide diuretics (increased risk of hypercalcaemia), Digoxin/other cardiac glycosides (arrhythmia risk with hypercalcaemia), Anticonvulsants like phenytoin/phenobarbital and rifampicin (reduced vitamin D effect), Cholestyramine/orlistat (reduced absorption of vitamin D), Corticosteroids (reduced vitamin D effect), Magnesium-containing antacids (risk of hypermagnesaemia in renal impairment)

Store below 25°C, protect from light, do not freeze. Keep in original pack and out of reach of children.

Uprise D3 6L Injection 1ml, Tayo 60K/6L Vitamin D3 Injection 1ml, Calcirol 6L Injection 1ml, Depura 6L Injection 1ml, D3 Must 6L Injection 1ml