Do not use if allergic to iodine/povidone-iodine. Avoid prolonged or extensive use, especially on large wounds/burns, as iodine can be absorbed and may affect thyroid function. Use with caution in thyroid disorders, kidney disease, and in patients on lithium therapy. Not for deep puncture wounds, animal bites or serious burns unless directed by a doctor. Stop use and seek medical advice if irritation, swelling, rash or symptoms of allergy occur.