Biotretin 10MG Cap

Capsule

Treatment of severe acne (nodular/cystic acne) that is resistant to adequate courses of standard therapy including systemic antibiotics and topical treatments

Isotretinoin is an oral retinoid that reduces sebum (oil) production by shrinking sebaceous glands. It also normalizes skin cell shedding in follicles and has anti-inflammatory effects, thereby reducing comedones and acne lesions.

Take the capsule exactly as prescribed by a dermatologist, usually once or twice daily with food (preferably a fatty meal) and water; swallow whole without crushing or chewing. Use for the prescribed duration; regular follow-up and lab monitoring may be required.

Dry lips, dry skin, dry eyes, nosebleeds, skin peeling, photosensitivity, headache, muscle/joint pain, increased liver enzymes, increased triglycerides, mood changes

Highly teratogenic: must not be used in pregnancy; effective contraception required before, during and after therapy as advised; discontinue and seek urgent medical advice if pregnancy occurs. Avoid blood donation during treatment and for at least 1 month after stopping. Monitor liver function and lipids; use with caution in liver disease, hyperlipidemia, diabetes, depression or other psychiatric illness. Avoid excessive sun exposure; use sunscreen. Do not use with tetracyclines (risk of intracranial hypertension). Report severe headache/visual changes, severe abdominal pain, persistent diarrhea/bleeding, or significant mood changes.

Tetracyclines (e.g., doxycycline, minocycline), vitamin A supplements/other retinoids, alcohol (increases risk of hypertriglyceridemia/hepatotoxicity), hepatotoxic medicines, corticosteroids (may increase risk of osteoporosis), phenytoin (bone effects)

Store below 25°C in a cool, dry place, protected from light and moisture. Keep in original packaging and out of reach of children.

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