Drug | Syrup

Epilepsy and seizure disorders (often pediatric use) for seizure prevention and control as prescribed

Phenobarbitone increases GABA-mediated inhibition and reduces excitatory neuronal activity. This stabilizes electrical activity in the brain and helps prevent seizures.

Use only as prescribed. Measure dose with a calibrated measuring cup/spoon or oral syringe; do not use household spoon. Give at the same time daily; do not stop abruptly.

Sleepiness, dizziness, sedation, irritability, hyperactivity (in children), nausea, rash

Habit-forming potential; use strictly under medical supervision. Sudden withdrawal can trigger seizures. Can cause significant drowsiness and impaired coordination. Watch for allergic reactions or severe skin rash; seek urgent care if occurs. Dose adjustments may be needed in liver impairment; avoid alcohol.

Alcohol and other CNS depressants, oral contraceptives (reduced efficacy), warfarin, corticosteroids, doxycycline, antiretrovirals, azole antifungals, valproate, phenytoin/carbamazepine

Store below 25°C, away from light. Keep bottle tightly closed; do not freeze. Keep out of reach of children.

Phenobarb Syrup, Phenobarbitone Syrup (generic), Luminal Elixir/Syrup, Epilex Phenobarbitone Syrup, Barbitone Syrup