Drug | Tablet

Treatment of mixed dyslipidemia (high LDL cholesterol and high triglycerides) when lifestyle changes alone are insufficient; helps reduce risk of cardiovascular events in high‑risk patients as advised by a doctor.

Rosuvastatin is a statin that inhibits HMG‑CoA reductase, reducing cholesterol synthesis in the liver and lowering LDL and total cholesterol while modestly raising HDL. Fenofibrate activates PPAR‑α, increasing breakdown and clearance of triglyceride-rich lipoproteins and improving HDL.

Take by mouth exactly as prescribed, usually once daily. Take at the same time each day; may be taken with or without food (follow your doctor’s advice). Swallow whole with water; do not crush or chew. Continue diet/exercise and regular lipid monitoring.

Headache, nausea, abdominal pain, constipation, diarrhea, dizziness, muscle pain (myalgia), weakness, increased liver enzymes

Risk of muscle injury (myopathy/rhabdomyolysis) increases with statin+fibrate therapy—seek medical help for unexplained muscle pain/weakness, fever or dark urine. Use with caution/avoid in active liver disease, severe kidney impairment, gallbladder disease, hypothyroidism not controlled, and in elderly. Periodic liver function tests, kidney function and lipid profile may be required. Stop and consult doctor if jaundice, severe abdominal pain, pancreatitis symptoms or allergic reactions occur.

Warfarin/other anticoagulants (increased bleeding risk; monitor INR), cyclosporine (increases statin levels; avoid/close monitoring), gemfibrozil/other fibrates or high-dose niacin (higher myopathy risk), colchicine (myopathy risk), protease inhibitors and some antivirals (raise statin exposure), erythromycin/clarithromycin (may increase muscle risk), antacids containing aluminum/magnesium (reduce rosuvastatin absorption; separate dosing), bile acid sequestrants (separate dosing)

Store at room temperature (below 25°C), in original pack, protected from moisture and light. Keep out of reach of children.

Rosuvas F 10/160 Tablet, Rozavel F 10/160 Tablet, Roseday F 10/160 Tablet, Crestor-F 10/160 Tablet, Rosufit-F 10/160 Tablet