Depression; neuropathic (nerve) pain; prevention of migraine/tension-type headache (as prescribed); certain anxiety/sleep disorders (off-label, doctor-directed)
How It Works
Amitriptyline is a tricyclic antidepressant that increases levels of serotonin and noradrenaline in the brain by inhibiting their reuptake, improving mood. It also modulates pain pathways and has sedative effects, which can help in neuropathic pain and sleep.
Directions for Use
Take exactly as prescribed. Usually taken by mouth once daily, preferably at bedtime due to drowsiness; can be taken with or without food. Swallow whole with water. Do not stop suddenly—dose is usually tapered by the doctor.
Side Effects
Drowsiness, dizziness, dry mouth, constipation, blurred vision, weight gain, increased appetite, nausea, difficulty urinating, sweating, fast heartbeat, low blood pressure on standing
Warnings & Precautions
May cause marked drowsiness—avoid driving/operating machinery until effects are known. Risk of suicidal thoughts/behavior especially at start of therapy or dose changes; monitor closely. Avoid in recent heart attack; use caution in heart disease, arrhythmias, glaucoma (narrow-angle), urinary retention/prostate enlargement, seizures, bipolar disorder/mania, liver disease, and elderly (higher anticholinergic effects/fall risk). Do not use with MAO inhibitors (or within 14 days). Serotonin syndrome risk with serotonergic medicines. Do not stop abruptly (withdrawal symptoms).
Habit Forming
No
ManufacturerDR.REDDYS
BrandDr Reddys Laboratories Ltd
Drug Interactions
MAO inhibitors (contraindicated), other antidepressants/SSRIs/SNRIs (e.g., fluoxetine, sertraline) and triptans (serotonin syndrome risk), alcohol/CNS depressants (increased sedation), anticholinergics (increased side effects), QT-prolonging drugs (e.g., certain antiarrhythmics/antipsychotics/macrolides), antihypertensives (additive hypotension), cimetidine (increases levels), carbamazepine/phenytoin (may reduce levels), tramadol (seizure/serotonin syndrome risk), warfarin (may alter anticoagulant effect)
Storage Instructions
Store at room temperature (below 25°C), protected from light and moisture. Keep in original pack and out of reach of children.
Depression; neuropathic (nerve) pain; prevention of migraine/tension-type headache (as prescribed); certain anxiety/sleep disorders (off-label, doctor-directed)
What are the side effects?
Drowsiness, dizziness, dry mouth, constipation, blurred vision, weight gain, increased appetite, nausea, difficulty urinating, sweating, fast heartbeat, low blood pressure on standing
How does this medicine work?
Amitriptyline is a tricyclic antidepressant that increases levels of serotonin and noradrenaline in the brain by inhibiting their reuptake, improving mood. It also modulates pain pathways and has sedative effects, which can help in neuropathic pain and sleep.
How should I use this medicine?
Take exactly as prescribed. Usually taken by mouth once daily, preferably at bedtime due to drowsiness; can be taken with or without food. Swallow whole with water. Do not stop suddenly—dose is usually tapered by the doctor.
How should I store this medicine?
Store at room temperature (below 25°C), protected from light and moisture. Keep in original pack and out of reach of children.
Do I need a prescription for this product?
Yes, this product requires a valid prescription (Rx). Upload it during checkout when prompted.
Can prices or availability change?
Yes. Prices and availability can change based on inventory and serviceability. The latest details are shown at checkout.
How do I place an order?
Select a variant, add to cart, enter delivery address, upload prescription if required, and pay securely.
Manufacturer & Brand
Brand:Dr Reddys Laboratories Ltd
Manufacturer:DR.REDDYS
HSN Code:30049069
Alternatives
Alternatives are suggested by pharmacists after reviewing your order and prescription.
Disclaimer: Product information is for awareness only and does not replace medical advice. For Rx medicines, a valid prescription is required. Consult your doctor or pharmacist for personalized guidance.
Sources: Manufacturer labeling/pack insert, established medical literature (TCA pharmacology), standard drug references (e.g., BNF/DrugBank), Indian regulatory/marketed product information
