Overview
Distributor inventory | Capsule
Uses & Benefits
Treatment of acid reflux (GERD), heartburn, peptic/duodenal ulcer, gastritis/acid-related indigestion; prevention of NSAID-induced ulcers; part of H. pylori eradication therapy (with antibiotics).
How It Works
Omeprazole is a proton pump inhibitor (PPI). It irreversibly blocks the gastric H+/K+ ATPase (proton pump) in stomach parietal cells, reducing acid production and allowing ulcers/erosions to heal.
Directions for Use
Capsule for oral use. Take exactly as prescribed, usually once daily 30–60 minutes before food (preferably before breakfast). Swallow whole; do not crush or chew. If on twice daily dosing, take before breakfast and before dinner.
Side Effects
Headache, nausea, vomiting, diarrhea, abdominal pain, flatulence, constipation, dizziness
Warnings & Precautions
Long-term use may increase risk of vitamin B12 deficiency, low magnesium, bone fractures, and infections (e.g., C. difficile diarrhea). Seek medical help for black/tarry stools, blood in vomit, severe persistent diarrhea, unexplained weight loss, or difficulty swallowing. Use with caution in liver disease. May mask symptoms of gastric cancer—evaluate alarm symptoms before prolonged use.
Drug Interactions
Clopidogrel (reduced effect), warfarin (may increase INR), phenytoin, diazepam, digoxin, methotrexate (high dose), tacrolimus, atazanavir/nelfinavir (reduced absorption), ketoconazole/itraconazole/iron salts (reduced absorption)