Distributor inventory
Glimepiride 1 mg + Metformin (as sustained/extended-release) 500 mg
Type 2 diabetes mellitus (adult) to improve blood glucose control when diet and exercise alone are inadequate; used when combination therapy is required.
Glimepiride (a sulfonylurea) increases insulin release from pancreatic beta cells and improves peripheral insulin sensitivity. Metformin (a biguanide) decreases hepatic glucose production and reduces intestinal glucose absorption while improving insulin sensitivity.
Oral tablet. Take exactly as prescribed, usually once daily with food (preferably with/after breakfast) to reduce stomach upset and risk of low sugar. Swallow whole; do not crush/chew (ER component). Monitor blood glucose regularly.
Common side effects of AMARYL MP 1MG may include:
Risk of hypoglycaemia (higher with missed meals, strenuous exercise, alcohol, elderly, kidney/liver impairment). Metformin may rarely cause lactic acidosis—seek urgent care for rapid breathing, severe weakness, muscle pain, unusual sleepiness. Avoid/use with caution in renal impairment; kidney function should be assessed before and during therapy. Temporary discontinuation may be needed around major surgery or iodinated contrast studies. Use caution in hepatic disease, heart failure, dehydration; monitor HbA1c and glucose.
