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Prescription requiredMerck LtdAntidiabetic
Carbophage XR 500
Metformin hydrochloride prolonged-release 500 mg
₹21MRP ₹225% offIn stock
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Carbophage XR 500 is used for type 2 diabetes mellitus (to control blood sugar), insulin resistance/prediabetes as advised by doctor; may be used alone or with other antidiabetic medicines.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Licensed pharmacyPharmacist-verified orderDelivered across India
Key details
Salt: Metformin hydrochloride prolonged-release 500 mg
Available variants: NA 10`S
Best price: ₹21
MRP: ₹22
Prescription: Required
Manufacturer: MERCK PHARMA
Ordering notes
Standard delivery across India. No same-day delivery nationally.
Chennai express delivery is possible and chargeable. Learn more
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy
Composition of Carbophage XR 500
Carbophage XR 500 contains Metformin hydrochloride prolonged-release 500 mg. It belongs to the Biguanide (antihyperglycemic), extended-release formulation class of medicines.
Uses of Carbophage XR 500
- Type 2 diabetes mellitus (to control blood sugar)
- insulin resistance/prediabetes as advised by doctor; may be used alone or with other antidiabetic medicines
Key benefits
- Helps control fasting and post-meal blood glucose
- Improves insulin sensitivity
- Lower risk of hypoglycaemia when used alone
- May support modest weight neutrality/weight reduction
- Once-daily extended-release dosing improves tolerability
How Carbophage XR 500 works
Metformin reduces glucose production by the liver and decreases intestinal absorption of glucose. It also improves the body’s sensitivity to insulin, helping cells use glucose better and lowering blood sugar levels.
How to take Carbophage XR 500
Take orally as advised by your doctor, usually once daily with the evening meal or with food. Swallow the XR tablet whole; do not crush, break, or chew. Dose is adjusted based on blood sugar and tolerance; continue diet and exercise recommendations.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
Missed dose and overdose
If you miss a dose
Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.
If you take too much
An overdose of this medicine can cause a dangerous build-up of acid in the blood, with vomiting, severe weakness and laboured breathing. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Side effects of Carbophage XR 500
Most side effects of Carbophage XR are mild and settle as the body adjusts. Reported side effects include:
- nausea
- diarrhoea
- abdominal pain
- loss of appetite
- metallic taste
- vomiting
- headache
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
Safety advice for Carbophage XR 500
| Pregnancy | Consult doctor (use only if clearly needed; insulin is often preferred in pregnancy) |
|---|---|
| Breastfeeding | Consult your doctor before using this while breastfeeding. |
| Alcohol | Avoid (increases risk of lactic acidosis and may affect blood sugar) |
| Driving | Not expected to affect your ability to drive. |
| Kidney | Consult your doctor if you have kidney disease. |
| Liver | Consult your doctor if you have liver disease. |
| Habit forming | No |
Warnings and precautions
Not for type 1 diabetes or diabetic ketoacidosis. Risk of lactic acidosis (rare but serious), higher in kidney impairment, severe dehydration, severe infection, heavy alcohol use, liver disease, or heart/respiratory failure—seek urgent care for weakness, muscle pain, breathing difficulty, unusual sleepiness, stomach discomfort. Use with caution/avoid in significant renal impairment; kidney function should be checked before and during treatment. Temporarily stop before/after iodinated contrast imaging and major surgery as advised. Long-term use may reduce vitamin B12 levels; monitor if anaemia/neuropathy symptoms. Hypoglycaemia is uncommon with metformin alone but can occur when combined with insulin/sulfonylureas.
Do not take Carbophage XR if
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with severe kidney disease, severe liver disease, or an acute illness causing dehydration. Not for people who have had diabetic ketoacidosis.
Interactions with other medicines
iodinated contrast media, alcohol, insulin and sulfonylureas (increased hypoglycaemia risk), cimetidine, carbonic anhydrase inhibitors (e.g., topiramate/acetazolamide) (increased acidosis risk), diuretics and ACE inhibitors/ARBs (may affect kidney function), corticosteroids and sympathomimetics (may raise blood sugar)
How to store Carbophage XR 500
Store below 25°C in a dry place, protected from moisture and light. Keep in original blister pack and out of reach of children.
Expert advice for Carbophage XR 500
Take it with or just after food to reduce stomach upset. Keep taking it even when your sugar readings look normal — that is the medicine working. Continue your diet and physical activity; this medicine works alongside them, not instead of them.
Manufacturer and class
- Manufacturer:
- MERCK PHARMA
- Therapeutic class:
- Antidiabetic
- Drug class:
- Biguanide (antihyperglycemic), extended-release formulation
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Carbophage XR 500 FAQs
What is Carbophage XR 500 used for?
Carbophage XR 500 is commonly used for Type 2 diabetes mellitus (to control blood sugar), insulin resistance/prediabetes as advised by doctor; may be used alone or with other antidiabetic medicines. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Carbophage XR 500?
Carbophage XR 500 contains Metformin hydrochloride prolonged-release 500 mg. If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Carbophage XR 500?
Take orally as advised by your doctor, usually once daily with the evening meal or with food. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Carbophage XR 500 work?
Metformin reduces glucose production by the liver and decreases intestinal absorption of glucose.
Is Carbophage XR 500 a prescription medicine?
Yes. Carbophage XR 500 is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Carbophage XR 500?
The side effects reported most often with Carbophage XR are nausea, diarrhoea, abdominal pain, loss of appetite, metallic taste. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Carbophage XR 500 be taken during pregnancy?
Consult doctor (use only if clearly needed; insulin is often preferred in pregnancy) Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Carbophage XR.
Can I drink alcohol while taking Carbophage XR 500?
Avoid (increases risk of lactic acidosis and may affect blood sugar)
What if I miss a dose of Carbophage XR 500?
Take it as soon as you remember.
Is Carbophage XR 500 habit forming?
No. Carbophage XR 500 is not known to be habit forming when taken as prescribed.
How much does Carbophage XR 500 cost on PingMeDoc Pharmacy?
Carbophage XR 500 starts at ₹21 (MRP ₹22) on PingMeDoc Pharmacy. Available in NA 10`S. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Carbophage XR 500?
Carbophage XR 500 is manufactured by MERCK PHARMA. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Carbophage XR 500 delivered?
Carbophage XR 500 is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.
Carbophage XR 500, Quick facts
- Salt
- Metformin hydrochloride prolonged-release 500 mg
- Best price
- ₹21
- MRP
- ₹22
- Prescription
- Required (Rx)
- Schedule
- Schedule H
- Brand
- Merck Ltd
- Manufacturer
- MERCK PHARMA
- Therapeutic class
- Antidiabetic
- Drug class
- Biguanide (antihyperglycemic), extended-release formulation
- Habit forming
- No
- Variants
- NA 10`S
- Delivery
- Standard across India
References
Compiled from the manufacturer's prescribing information and the sources below, and reviewed by a registered medical practitioner. It does not replace your own doctor's advice.
- Manufacturer labeling, established medical literature, standard diabetes treatment guidelines
- Indian regulatory/pack information conventions
- Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
- National List of Essential Medicines (NLEM) 2022, Government of India.
- Manufacturer's package insert / prescribing information for Carbophage XR 500.
- World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.
Next steps
Safety disclaimer
Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.