Prescription requiredAntidiabetic

Daparyl M 5/1000 Tab — Side Effects & Warnings

Known side effects of Daparyl M 5/1000 Tab include Nausea,diarrhoea,abdominal discomfort,loss of appetite,genital fungal infection,urinary tract infection,increased urination,thirst,dizziness,headache. Not everyone experiences these side effects.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated June 2026

Common Side Effects

Nausea
diarrhoea
abdominal discomfort
loss of appetite
genital fungal infection
urinary tract infection
increased urination
thirst
dizziness
headache

This is not an exhaustive list. Consult your doctor if you notice any unusual symptoms.

Important Warnings

Not for type 1 diabetes. Risk of lactic acidosis with metformin (higher risk in kidney impairment, dehydration, severe infection, heavy alcohol use, liver disease, heart failure, hypoxia); seek urgent care for fast breathing, severe weakness, abdominal pain, drowsiness. Dapagliflozin may cause genital mycotic infections, UTIs, volume depletion/low BP, and rare ketoacidosis (can occur with near-normal sugars); stop and seek care if nausea/vomiting, abdominal pain, rapid breathing. Assess renal function before and during therapy; dose/continuation depends on eGFR and product label. Temporarily withhold during acute illness, prolonged fasting, major surgery, or dehydration. Hold metformin around iodinated contrast procedures as per clinician advice. Monitor for hypoglycaemia if used with insulin/sulfonylureas.

Drug Interactions

Daparyl M 5/1000 Tab may interact with the following:

Alcohol (increases lactic acidosis risk)
insulin and sulfonylureas (increased hypoglycaemia)
diuretics/antihypertensives (enhanced dehydration/hypotension)
iodinated contrast media (lactic acidosis risk—temporary stop)
carbonic anhydrase inhibitors e.g. topiramate/acetazolamide (metabolic acidosis risk)
cimetidine (may increase metformin levels)
rifampicin (may alter dapagliflozin exposure)
NSAIDs/ACE inhibitors/ARBs (renal function changes—monitor)

Always tell your doctor about all medicines you are taking, including over-the-counter drugs and supplements.

Pregnancy Safety

Not recommended; consult doctor (insufficient safety data and potential fetal risk especially in 2nd/3rd trimester)

Alcohol Interaction

Avoid or use with caution; alcohol increases risk of lactic acidosis and hypoglycaemia

Habit Forming

Storage

Store below 25°C in a cool, dry place. Protect from moisture and direct light. Keep in original blister pack and out of reach of children.

Daparyl M 5/1000 Tab — Safety Summary

Composition: Dapagliflozin 5 mg + Metformin Hydrochloride 1000 mg (usually extended-release)
Prescription: Required (Rx)
Pregnancy: Not recommended; consult doctor (insufficient safety data and potential fetal risk especially in 2nd/3rd trimester)
Alcohol: Avoid or use with caution; alcohol increases risk of lactic acidosis and hypoglycaemia
Habit forming: No

Daparyl M 5/1000 Tab — Safety FAQs

What should I do if I experience side effects?

Mild side effects often resolve on their own. If side effects are severe or persistent, stop the medicine and consult your doctor immediately.

Are all listed side effects common?

No. Some side effects are common while others are rare. Not everyone experiences side effects. Consult your doctor if you are concerned.

Can I take this medicine with other drugs?

Some medicines interact with each other. Always inform your doctor about all medicines you are currently taking.

When should I seek emergency help?

Seek immediate medical attention if you experience severe allergic reactions (difficulty breathing, swelling of face/throat), chest pain, or any life-threatening symptoms.

Get help from a doctor

Consult a doctor

Discuss side effects with a qualified doctor online.

View all medicines

Full product details for Daparyl M 5/1000 Tab.

Lab tests

Book tests to monitor your health while on medication.

Safety disclaimer

This information is for educational purposes only and is not a substitute for professional medical advice. If you experience severe side effects, seek medical attention immediately.

Daparyl M 5/1000 Tab — Side Effects & Warnings

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated June 2026