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Prescription requiredIntas Pharmaceuticals LtdAntidiabetic
Daparyl M 5/1000 Tablet
Dapagliflozin 5 mg + Metformin Hydrochloride 1000 mg (usually extended-release)
₹107MRP ₹1125% offIn stock
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Daparyl M 5/1000 Tablet is used for type 2 diabetes mellitus (as an adjunct to diet and exercise) to improve glycaemic control when dual therapy is appropriate or when patients are uncontrolled on metformin or an SGLT2 inhibitor alone.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Licensed pharmacyPharmacist-verified orderDelivered across India
Key details
Salt: Dapagliflozin 5 mg + Metformin Hydrochloride 1000 mg (usually extended-release)
Available variants: tablet 5mg + 1000mg 10`S
Best price: ₹107 (₹10.67 per tablet)
MRP: ₹112
Prescription: Required
Manufacturer: INTAS PHARMACEUTICALS`
Ordering notes
Standard delivery across India. No same-day delivery nationally.
Chennai express delivery is possible and chargeable. Learn more
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy
Composition of Daparyl M 5/1000 Tablet
Daparyl M 5/1000 Tablet contains Dapagliflozin 5 mg + Metformin Hydrochloride 1000 mg (usually extended-release). It belongs to the SGLT2 inhibitor + Biguanide class of medicines.
Uses of Daparyl M 5/1000 Tablet
Type 2 diabetes mellitus (as an adjunct to diet and exercise) to improve glycaemic control when dual therapy is appropriate or when patients are uncontrolled on metformin or an SGLT2 inhibitor alone
Key benefits
- Lowers HbA1c and fasting/postprandial glucose
- Helps weight reduction or weight neutrality
- Lowers risk of hypoglycaemia when used without insulin/sulfonylurea
- May provide cardiovascular and renal protective benefits associated with SGLT2 inhibitors
How Daparyl M 5/1000 Tablet works
Dapagliflozin is an SGLT2 inhibitor that lowers blood glucose by increasing urinary glucose excretion from the kidneys. Metformin reduces hepatic glucose production and improves insulin sensitivity, decreasing intestinal glucose absorption and improving peripheral glucose uptake.
How to take Daparyl M 5/1000 Tablet
Oral tablet. Take exactly as prescribed; commonly taken once daily with food (preferably with the evening meal if extended-release) to reduce stomach upset. Swallow whole; do not crush/chew if ER. Maintain adequate hydration; monitor blood glucose as advised.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
Missed dose and overdose
If you miss a dose
Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.
If you take too much
An overdose of this medicine can cause dehydration and a fall in blood pressure. It can cause a dangerous build-up of acid in the blood, with vomiting, severe weakness and laboured breathing. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Side effects of Daparyl M 5/1000 Tablet
Most side effects of Daparyl M 5/1000 are mild and settle as the body adjusts. Reported side effects include:
- Nausea
- diarrhoea
- abdominal discomfort
- loss of appetite
- genital fungal infection
- urinary tract infection
- increased urination
- thirst
- dizziness
- headache
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
Safety advice for Daparyl M 5/1000 Tablet
| Pregnancy | Not recommended; consult doctor (insufficient safety data and potential fetal risk especially in 2nd/3rd trimester) |
|---|---|
| Breastfeeding | Not recommended while breastfeeding. |
| Alcohol | Avoid or use with caution; alcohol increases risk of lactic acidosis and hypoglycaemia |
| Driving | May cause drowsiness or affect your concentration. Do not drive until you know how it affects you. |
| Kidney | Consult your doctor if you have kidney disease. |
| Liver | Consult your doctor if you have liver disease. |
| Habit forming | No |
Warnings and precautions
Not for type 1 diabetes. Risk of lactic acidosis with metformin (higher risk in kidney impairment, dehydration, severe infection, heavy alcohol use, liver disease, heart failure, hypoxia); seek urgent care for fast breathing, severe weakness, abdominal pain, drowsiness. Dapagliflozin may cause genital mycotic infections, UTIs, volume depletion/low BP, and rare ketoacidosis (can occur with near-normal sugars); stop and seek care if nausea/vomiting, abdominal pain, rapid breathing. Assess renal function before and during therapy; dose/continuation depends on eGFR and product label. Temporarily withhold during acute illness, prolonged fasting, major surgery, or dehydration. Hold metformin around iodinated contrast procedures as per clinician advice. Monitor for hypoglycaemia if used with insulin/sulfonylureas.
Do not take Daparyl M 5/1000 if
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for type 1 diabetes or for diabetic ketoacidosis. Not for people with severe kidney disease. Not for people with severe kidney disease, severe liver disease, or an acute illness causing dehydration. Not for people who have had diabetic ketoacidosis.
Interactions with other medicines
Alcohol (increases lactic acidosis risk),insulin and sulfonylureas (increased hypoglycaemia),diuretics/antihypertensives (enhanced dehydration/hypotension),iodinated contrast media (lactic acidosis risk—temporary stop),carbonic anhydrase inhibitors e.g. topiramate/acetazolamide (metabolic acidosis risk),cimetidine (may increase metformin levels),rifampicin (may alter dapagliflozin exposure),NSAIDs/ACE inhibitors/ARBs (renal function changes—monitor)
How to store Daparyl M 5/1000 Tablet
Store below 25°C in a cool, dry place. Protect from moisture and direct light. Keep in original blister pack and out of reach of children.
Expert advice for Daparyl M 5/1000 Tablet
Take it in the morning so the extra urine does not disturb your sleep. Keep up your fluid intake and maintain genital hygiene. Tell any doctor treating you for an acute illness that you take this medicine. Take it with or just after food to reduce stomach upset. Keep taking it even when your sugar readings look normal — that is the medicine working. Continue your diet and physical activity; this medicine works alongside them, not instead of them.
Manufacturer and class
- Manufacturer:
- INTAS PHARMACEUTICALS`
- Therapeutic class:
- Antidiabetic
- Drug class:
- SGLT2 inhibitor + Biguanide
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Daparyl M 5/1000 Tablet FAQs
What is Daparyl M 5/1000 Tablet used for?
Daparyl M 5/1000 Tablet is commonly used for Type 2 diabetes mellitus (as an adjunct to diet and exercise) to improve glycaemic control when dual therapy is appropriate or when patients are uncontrolled on metformin or an SGLT2 inhibitor alone. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Daparyl M 5/1000 Tablet?
Daparyl M 5/1000 Tablet contains Dapagliflozin 5 mg + Metformin Hydrochloride 1000 mg (usually extended-release). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Daparyl M 5/1000 Tablet?
Oral tablet. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Daparyl M 5/1000 Tablet work?
Dapagliflozin is an SGLT2 inhibitor that lowers blood glucose by increasing urinary glucose excretion from the kidneys.
Is Daparyl M 5/1000 Tablet a prescription medicine?
Yes. Daparyl M 5/1000 Tablet is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Daparyl M 5/1000 Tablet?
The side effects reported most often with Daparyl M 5/1000 are Nausea, diarrhoea, abdominal discomfort, loss of appetite, genital fungal infection. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Daparyl M 5/1000 Tablet be taken during pregnancy?
Not recommended; consult doctor (insufficient safety data and potential fetal risk especially in 2nd/3rd trimester) Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Daparyl M 5/1000.
Can I drink alcohol while taking Daparyl M 5/1000 Tablet?
Avoid or use with caution; alcohol increases risk of lactic acidosis and hypoglycaemia
What if I miss a dose of Daparyl M 5/1000 Tablet?
Take it as soon as you remember.
Is Daparyl M 5/1000 Tablet habit forming?
No. Daparyl M 5/1000 Tablet is not known to be habit forming when taken as prescribed.
How much does Daparyl M 5/1000 Tablet cost on PingMeDoc Pharmacy?
Daparyl M 5/1000 Tablet starts at ₹107 (MRP ₹112) on PingMeDoc Pharmacy. Available in tablet 5mg + 1000mg 10`S. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Daparyl M 5/1000 Tablet?
Daparyl M 5/1000 Tablet is manufactured by INTAS PHARMACEUTICALS`. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Daparyl M 5/1000 Tablet delivered?
Daparyl M 5/1000 Tablet is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.
Daparyl M 5/1000 Tablet, Quick facts
- Salt
- Dapagliflozin 5 mg + Metformin Hydrochloride 1000 mg (usually extended-release)
- Form
- tablet
- Best price
- ₹107 (₹10.67 per tablet)
- MRP
- ₹112
- Prescription
- Required (Rx)
- Schedule
- Schedule H
- Brand
- Intas Pharmaceuticals Ltd
- Manufacturer
- INTAS PHARMACEUTICALS`
- Therapeutic class
- Antidiabetic
- Drug class
- SGLT2 inhibitor + Biguanide
- Habit forming
- No
- Variants
- tablet 5mg + 1000mg 10`S
- Delivery
- Standard across India
References
Compiled from the manufacturer's prescribing information and the sources below, and reviewed by a registered medical practitioner. It does not replace your own doctor's advice.
- Manufacturer labeling/SmPC,CDSCO approved drug information,Indian Pharmacopoeia,established medical literature (ADA guidelines, standard pharmacology texts)
- Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
- National List of Essential Medicines (NLEM) 2022, Government of India.
- Manufacturer's package insert / prescribing information for Daparyl M 5/1000 Tablet.
- World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.
Next steps
Safety disclaimer
Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.