Drug | Tablet
Sodium valproate 199.8 mg + Valproic acid 87 mg (equivalent to valproate semisodium 300 mg) prolonged release
Epilepsy/seizure disorders, bipolar disorder (mania) as prescribed, prevention of migraine (selected patients as prescribed)
Valproate increases inhibitory GABA neurotransmission and reduces abnormal electrical activity in the brain. Prolonged release helps maintain stable plasma concentrations for ongoing seizure and mood control.
Take as prescribed with food if needed. Swallow whole; do not crush or chew prolonged-release tablets. Do not stop abruptly; periodic lab monitoring (LFTs, CBC) may be needed.
Common side effects of Encorate Chrono 300 Tablet may include:
Not recommended in pregnancy; high teratogenic risk and developmental harm. Risk of serious liver injury, pancreatitis, hyperammonemia and low platelets; watch for jaundice, severe abdominal pain, vomiting, bruising/bleeding or altered sensorium. Use caution in liver disease and mitochondrial disorders.
