Prescription requiredAntidiabetic (Dpp-4 Inhibitor + Biguanide)

Janumet 50/1000 Tablet — Uses, Dosage & Benefits

Janumet 50/1000 Tablet is used for Controls blood sugar levels, improves insulin production, reduces glucose production in the liver.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated August 2026

Sitagliptin (50 mg) + Metformin (1000 mg)

Decreases hepatic glucose production and improves insulin sensitivity; acts in liver and gut.

Take as directed by the physician, with or after food. Do not crush or chew the tablet. Drink plenty of fluids while taking this medication.

Always follow your doctor's prescription. Do not self-medicate.

Janumet 50/1000 Tablet — Quick Facts

How should I take this medicine?

Follow the dosage prescribed by your doctor. Do not alter the dose without medical advice.

Can I take this medicine without a prescription?

Prescription-required medicines need a valid Rx. OTC medicines can be purchased directly.

What if I miss a dose?

Take the missed dose as soon as you remember, unless it is close to your next scheduled dose. Do not double the dose.

How long does it take to show effect?

The time to show effect varies by medicine and condition. Consult your doctor for specific timelines.