Drug | Tablet
Dapagliflozin + Metformin
Type 2 diabetes mellitus: to improve glycaemic control as an add-on to diet and exercise in adults when treatment with both dapagliflozin and metformin is appropriate.
Dapagliflozin is an SGLT2 inhibitor that lowers blood glucose by increasing urinary glucose excretion via the kidneys and also promotes mild diuresis. Metformin reduces hepatic glucose production and improves insulin sensitivity, decreasing intestinal glucose absorption and improving peripheral glucose uptake.
Oral tablet. Take exactly as prescribed, usually once daily (or as directed) with food to reduce stomach upset; swallow whole with water. Maintain adequate hydration; follow diet/exercise advice and monitor blood glucose as advised.
Common side effects of Justoza M 10/500 Tablet may include:
Schedule H: use under medical supervision. Metformin may rarely cause lactic acidosis—risk increases with severe kidney disease, dehydration, sepsis, excessive alcohol use, liver disease, or hypoxia; stop and seek care if rapid breathing, severe weakness, abdominal pain, or unusual sleepiness occurs. Dapagliflozin may cause genital/urinary infections, volume depletion/low BP, and (rare) ketoacidosis even with near-normal sugars—seek urgent care for nausea/vomiting, abdominal pain, rapid breathing, confusion. Assess kidney function before and during therapy; not recommended in severe renal impairment; temporary interruption may be needed during acute illness, prolonged fasting, major surgery, or iodinated contrast procedures as per clinician advice. Monitor for hypoglycaemia when used with insulin or sulfonylureas.
