Prescription requiredAntihypertensive, Antianginal

Samlokind-2.5 10S — Side Effects & Warnings

Known side effects of Samlokind-2.5 10S include Swelling of ankles/feet (edema), headache, dizziness, flushing, fatigue, palpitations, nausea, abdominal pain, sleepiness. Not everyone experiences these side effects.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated August 2026

Common Side Effects

Swelling of ankles/feet (edema)
headache
dizziness
flushing
fatigue
palpitations
nausea
abdominal pain
sleepiness

This is not an exhaustive list. Consult your doctor if you notice any unusual symptoms.

Important Warnings

Use with caution in liver impairment (may need lower dose). May cause dizziness—avoid driving/operating machinery if affected. Monitor for excessive fall in blood pressure, worsening chest pain at start or dose increase, and swelling. Caution in heart failure and severe aortic stenosis. Not a substitute for emergency treatment of acute chest pain.

Drug Interactions

Samlokind-2.5 10S may interact with the following:

Other antihypertensives (additive BP lowering)
CYP3A4 inhibitors (e.g.
clarithromycin
erythromycin
ketoconazole
ritonavir) may increase amlodipine levels
CYP3A4 inducers (e.g.
rifampicin
phenytoin
carbamazepine) may reduce effect
simvastatin (limit dose as per prescriber)
grapefruit juice (may increase levels in some patients)

Always tell your doctor about all medicines you are taking, including over-the-counter drugs and supplements.

Pregnancy Safety

Consult doctor

Alcohol Interaction

Use with caution

Habit Forming

Storage

Store below 25°C, in a dry place away from light and moisture. Keep out of reach of children.

Samlokind-2.5 10S — Safety Summary

Composition: S-Amlodipine (2.5mg)
Prescription: Required (Rx)
Pregnancy: Consult doctor
Alcohol: Use with caution
Habit forming: No

Samlokind-2.5 10S — Safety FAQs

What should I do if I experience side effects?

Mild side effects often resolve on their own. If side effects are severe or persistent, stop the medicine and consult your doctor immediately.

Are all listed side effects common?

No. Some side effects are common while others are rare. Not everyone experiences side effects. Consult your doctor if you are concerned.

Can I take this medicine with other drugs?

Some medicines interact with each other. Always inform your doctor about all medicines you are currently taking.

When should I seek emergency help?

Seek immediate medical attention if you experience severe allergic reactions (difficulty breathing, swelling of face/throat), chest pain, or any life-threatening symptoms.

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Safety disclaimer

This information is for educational purposes only and is not a substitute for professional medical advice. If you experience severe side effects, seek medical attention immediately.