Prescription requiredAnti-inflammatory (IBD) / DMARD

Sazo 500 Tab — Side Effects & Warnings

Known side effects of Sazo 500 Tab include Nausea, vomiting, abdominal pain, loss of appetite, headache, dizziness, rash, fever, reversible low sperm count, orange/yellow discoloration of urine/skin, elevated liver enzymes. Not everyone experiences these side effects.

Common Side Effects

Nausea
vomiting
abdominal pain
loss of appetite
headache
dizziness
rash
fever
reversible low sperm count
orange/yellow discoloration of urine/skin
elevated liver enzymes

This is not an exhaustive list. Consult your doctor if you notice any unusual symptoms.

Important Warnings

Use only on prescription. Inform doctor if you have allergy to sulfonamides or salicylates, G6PD deficiency, liver or kidney disease, asthma, blood disorders, or intestinal/urinary obstruction. Can cause serious skin reactions (SJS/TEN), blood dyscrasias (low WBC/platelets), hepatotoxicity, and worsening of ulcerative colitis in rare cases—seek urgent care for rash, mouth ulcers, fever, sore throat, unusual bruising/bleeding, yellowing of eyes/skin. Regular monitoring of CBC and liver function is advised. May reduce folate levels—supplementation may be recommended. Avoid excessive sun exposure if photosensitivity occurs.

Drug Interactions

Sazo 500 Tab may interact with the following:

Methotrexate (increased toxicity risk)
azathioprine/6-mercaptopurine (myelosuppression risk)
warfarin (may alter anticoagulant effect)
digoxin (reduced absorption)
oral antidiabetic medicines (enhanced hypoglycaemia risk)
sulfonylureas
phenytoin (altered levels)
folic acid (reduced absorption)
certain antibiotics that alter gut flora (may change effect).

Always tell your doctor about all medicines you are taking, including over-the-counter drugs and supplements.

Pregnancy Safety

Use with caution / Consult doctor (often used when benefits outweigh risks; folate supplementation may be advised)

Alcohol Interaction

Use with caution (may increase risk of stomach upset and liver-related side effects)

Habit Forming

Storage

Store below 25°C in a dry place, protected from moisture and light. Keep in original blister pack and out of reach of children.

Sazo 500 Tab — Safety Summary

Composition: Sulfasalazine (500mg)
Prescription: Required (Rx)
Pregnancy: Use with caution / Consult doctor (often used when benefits outweigh risks; folate supplementation may be advised)
Alcohol: Use with caution (may increase risk of stomach upset and liver-related side effects)
Habit forming: No

Sazo 500 Tab — Safety FAQs

What should I do if I experience side effects?

Mild side effects often resolve on their own. If side effects are severe or persistent, stop the medicine and consult your doctor immediately.

Are all listed side effects common?

No. Some side effects are common while others are rare. Not everyone experiences side effects. Consult your doctor if you are concerned.

Can I take this medicine with other drugs?

Some medicines interact with each other. Always inform your doctor about all medicines you are currently taking.

When should I seek emergency help?

Seek immediate medical attention if you experience severe allergic reactions (difficulty breathing, swelling of face/throat), chest pain, or any life-threatening symptoms.

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Safety disclaimer

This information is for educational purposes only and is not a substitute for professional medical advice. If you experience severe side effects, seek medical attention immediately.