Supermet H Tablet

Composition of Supermet H Tablet

Supermet H Tablet contains Metoprolol Succinate (50mg) + Hydrochlorothiazide (12.5mg). It belongs to the Biguanide + Sulfonylurea + Thiazide diuretic class of medicines.

Uses of Supermet H Tablet

Type 2 diabetes mellitus with co-existing hypertension/edema; used to control blood sugar and help lower blood pressure as prescribed.

Key benefits

• Helps control fasting and post-meal blood sugar
• Improves insulin action and reduces glucose production
• Reduces excess fluid and helps lower blood pressure
• May reduce diabetes-related complications with good control

How Supermet H Tablet works

Metformin reduces glucose production in the liver and improves insulin sensitivity. Glimepiride increases insulin release from the pancreas. Hydrochlorothiazide is a thiazide diuretic that reduces fluid volume and lowers blood pressure by increasing urine output.

How to take Supermet H Tablet

Take by mouth as prescribed, usually once daily with food (preferably with/after breakfast) to reduce stomach upset. Swallow whole with water; take at the same time each day. Do not skip meals; monitor blood glucose regularly.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

If you miss a dose of Supermet H Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

If you take too much

An overdose of this medicine can cause a dangerously slow heartbeat, a severe fall in blood pressure, wheezing and fits. It can cause severe dehydration, a sharp fall in blood pressure and dangerous salt imbalances. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Supermet H Tablet

Most side effects of Supermet H are mild and settle as the body adjusts. Reported side effects include:

• Nausea
• vomiting
• diarrhea
• stomach pain
• loss of appetite
• dizziness
• headache
• increased urination
• dehydration
• low blood sugar (sweating
• tremor
• hunger)
• electrolyte imbalance (low potassium)
• rash

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Supermet H Tablet

Warnings and precautions

Risk of hypoglycaemia (higher with missed meals, excess exercise, alcohol, or other antidiabetics); monitor glucose. Metformin may rarely cause lactic acidosis—risk increases with kidney disease, dehydration, severe infection, heart/respiratory failure, or alcohol; avoid in severe renal impairment and stop temporarily during acute illness/dehydration. Hydrochlorothiazide may cause low potassium/sodium and increase uric acid (gout) and photosensitivity; monitor electrolytes and kidney function. Use caution in liver disease and in elderly; report severe weakness, muscle cramps, breathing difficulty, or persistent vomiting/diarrhea. Before iodinated contrast scans or major surgery, metformin may need to be withheld per doctor advice.

Do not take Supermet H if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with a very slow heart rate, certain heart block disorders, or uncontrolled heart failure. Generally avoided in severe asthma. Not for people who are unable to pass urine, or who are severely dehydrated.

Interactions with other medicines

Alcohol (increases hypoglycaemia/lactic acidosis risk), insulin/other antidiabetics (hypoglycaemia), corticosteroids and beta-agonists (raise glucose), thiazide/loop diuretics (electrolyte changes, may worsen glycaemia), ACE inhibitors/ARBs (may enhance glucose-lowering, affect potassium), NSAIDs (renal risk), iodinated contrast media (lactic acidosis risk with metformin), lithium (increased lithium levels with thiazides), digoxin (electrolyte-related toxicity), sulfonamide allergy cross-reactivity (HCTZ)

How to store Supermet H Tablet

Store below 25°C in a dry place, protected from light and moisture. Keep in original blister pack and out of reach of children.

Expert advice for Supermet H Tablet

It is a combination of two blood pressure lowering medications used for the treatment of high blood pressure. It can be taken with or without food. Do not stop taking Supermet H Tablet suddenly as it can cause your blood pressure to rise suddenly thereby increasing the risk of heart attack and stroke. It may cause dizziness. If this happens to you, get up slowly when rising from a sitting or lying position. It can hide symptoms of low blood sugar if you're diabetic. Monitor your blood sugar levels regularly. Supermet H Tablet may cause dehydration. Drink plenty of fluids and Inform your doctor if you develop extreme thirst, muscle weakness or very dry mouth.

Manufacturer and class

Manufacturer:

ABBOTT HEALTHCARE LIMITED

Therapeutic class:

Antidiabetic + Antihypertensive

Drug class:

Biguanide + Sulfonylurea + Thiazide diuretic