Prescription requiredThyroid hormone replacement

Thyrox 25 Tablet — Side Effects & Warnings

Known side effects of Thyrox 25 Tablet include Palpitations,fast heartbeat,anxiety,irritability,insomnia,headache,tremor,sweating,heat intolerance,weight loss,diarrhoea,nausea,menstrual irregularities,temporary hair loss (initially). Not everyone experiences these side effects.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated June 2026

Common Side Effects

Palpitations
fast heartbeat
anxiety
irritability
insomnia
headache
tremor
sweating
heat intolerance
weight loss
diarrhoea
nausea
menstrual irregularities
temporary hair loss (initially)

This is not an exhaustive list. Consult your doctor if you notice any unusual symptoms.

Important Warnings

Not for weight loss/obesity treatment; high doses can cause serious heart problems. Use with caution in heart disease (angina, arrhythmias), hypertension, elderly, osteoporosis, diabetes, and adrenal/pituitary insufficiency (ensure adrenal function treated before starting). Monitor TSH/T4 regularly; symptoms of overdose include chest pain, palpitations, nervousness, and excessive sweating—seek medical help. Contains narrow therapeutic index—do not interchange brands/doses without doctor’s advice.

Drug Interactions

Thyrox 25 Tablet may interact with the following:

Reduced absorption with iron salts
calcium carbonate
aluminium/magnesium antacids
sucralfate
cholestyramine/colestipol
sevelamer
orlistat
soy/high-fibre diets; increased effect of warfarin; may increase insulin/oral antidiabetic requirements; interactions with rifampicin
carbamazepine
phenytoin
phenobarbital (increase metabolism)
sertraline
amiodarone; timing interaction with proton pump inhibitors and coffee (may reduce absorption)

Always tell your doctor about all medicines you are taking, including over-the-counter drugs and supplements.

Pregnancy Safety

Generally safe (often required in pregnancy); dose adjustment and close TSH monitoring needed—consult doctor

Alcohol Interaction

Use with caution; no direct interaction known, but excessive alcohol may affect thyroid function and overall control

Habit Forming

Storage

Store below 25°C in a cool, dry place protected from light and moisture. Keep in original blister pack and out of reach of children.

Thyrox 25 Tablet — Safety Summary

Composition: Levothyroxine sodium 25 mcg (equivalent to Levothyroxine 25 mcg)
Prescription: Required (Rx)
Pregnancy: Generally safe (often required in pregnancy); dose adjustment and close TSH monitoring needed—consult doctor
Alcohol: Use with caution; no direct interaction known, but excessive alcohol may affect thyroid function and overall control
Habit forming: No

Thyrox 25 Tablet — Safety FAQs

What should I do if I experience side effects?

Mild side effects often resolve on their own. If side effects are severe or persistent, stop the medicine and consult your doctor immediately.

Are all listed side effects common?

No. Some side effects are common while others are rare. Not everyone experiences side effects. Consult your doctor if you are concerned.

Can I take this medicine with other drugs?

Some medicines interact with each other. Always inform your doctor about all medicines you are currently taking.

When should I seek emergency help?

Seek immediate medical attention if you experience severe allergic reactions (difficulty breathing, swelling of face/throat), chest pain, or any life-threatening symptoms.

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Safety disclaimer

This information is for educational purposes only and is not a substitute for professional medical advice. If you experience severe side effects, seek medical attention immediately.

Thyrox 25 Tablet — Side Effects & Warnings

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated June 2026