Prescription requiredCorticosteroid (anti-inflammatory/antiallergic; immunosuppressant)

Wysolone DT 20 Tablet — Side Effects & Warnings

Known side effects of Wysolone DT 20 Tablet include Increased appetite, indigestion/heartburn, nausea, mood changes/irritability, insomnia, fluid retention, increased blood sugar, weight gain, acne, increased sweating. Not everyone experiences these side effects.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated June 2026

Common Side Effects

Increased appetite
indigestion/heartburn
nausea
mood changes/irritability
insomnia
fluid retention
increased blood sugar
weight gain
acne
increased sweating

This is not an exhaustive list. Consult your doctor if you notice any unusual symptoms.

Important Warnings

Prescription steroid: long-term/high-dose use can cause adrenal suppression, Cushingoid features, osteoporosis, cataract/glaucoma, hypertension, diabetes worsening and increased infection risk. Avoid close contact with people who have infections (e.g., chickenpox/measles); seek medical advice if exposed. Use with caution in diabetes, hypertension, peptic ulcer disease, osteoporosis, glaucoma, psychiatric illness, liver disease and in elderly. Do not stop suddenly; taper under medical supervision. Live vaccines are generally avoided during immunosuppressive doses.

Drug Interactions

Wysolone DT 20 Tablet may interact with the following:

NSAIDs (increased GI ulcer/bleeding risk)
anticoagulants like warfarin (altered INR)
antidiabetic medicines/insulin (reduced effect)
diuretics/amphotericin B (hypokalemia)
rifampicin/phenytoin/carbamazepine (reduced steroid effect)
ketoconazole/macrolides (increased steroid levels)
cyclosporine (increased toxicity)
vaccines (reduced response; avoid live vaccines at immunosuppressive doses)

Always tell your doctor about all medicines you are taking, including over-the-counter drugs and supplements.

Pregnancy Safety

Use with caution / Consult doctor (use lowest effective dose; benefit-risk assessment required)

Alcohol Interaction

Use with caution (may increase risk of stomach irritation/ulcer and worsen side effects)

Habit Forming

Storage

Store below 25°C in a dry place, protected from moisture and light. Keep in original pack and out of reach of children.

Wysolone DT 20 Tablet — Safety Summary

Composition: Prednisolone (20mg)
Prescription: Required (Rx)
Pregnancy: Use with caution / Consult doctor (use lowest effective dose; benefit-risk assessment required)
Alcohol: Use with caution (may increase risk of stomach irritation/ulcer and worsen side effects)
Habit forming: No

Wysolone DT 20 Tablet — Safety FAQs

What should I do if I experience side effects?

Mild side effects often resolve on their own. If side effects are severe or persistent, stop the medicine and consult your doctor immediately.

Are all listed side effects common?

No. Some side effects are common while others are rare. Not everyone experiences side effects. Consult your doctor if you are concerned.

Can I take this medicine with other drugs?

Some medicines interact with each other. Always inform your doctor about all medicines you are currently taking.

When should I seek emergency help?

Seek immediate medical attention if you experience severe allergic reactions (difficulty breathing, swelling of face/throat), chest pain, or any life-threatening symptoms.

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Safety disclaimer

This information is for educational purposes only and is not a substitute for professional medical advice. If you experience severe side effects, seek medical attention immediately.

Wysolone DT 20 Tablet — Side Effects & Warnings

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated June 2026