Prescription requiredAntidiabetic

Zoryl M D 2/1000 Tab — Side Effects & Warnings

Known side effects of Zoryl M D 2/1000 Tab include Hypoglycaemia, nausea, vomiting, diarrhoea, abdominal pain, loss of appetite, metallic taste, dizziness, headache. Not everyone experiences these side effects.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated June 2026

Common Side Effects

Hypoglycaemia
nausea
vomiting
diarrhoea
abdominal pain
loss of appetite
metallic taste
dizziness
headache

This is not an exhaustive list. Consult your doctor if you notice any unusual symptoms.

Important Warnings

Risk of hypoglycaemia (especially with missed meals, alcohol, heavy exercise, elderly); carry glucose. Metformin can rarely cause lactic acidosis—risk increases with severe kidney disease, dehydration, sepsis, hypoxia, heart failure, liver disease, or excess alcohol; stop and seek care if rapid breathing, severe weakness, abdominal pain occur. Assess renal function before and during therapy; avoid if eGFR very low as per doctor. Temporarily stop metformin around iodinated contrast procedures or major surgery as advised. Use caution in G6PD deficiency (hemolysis risk with sulfonylureas).

Drug Interactions

Zoryl M D 2/1000 Tab may interact with the following:

Alcohol (increases hypoglycaemia and lactic acidosis risk)
insulin/other antidiabetics (additive hypoglycaemia)
beta-blockers (mask hypoglycaemia)
corticosteroids/thiazide diuretics/thyroid hormones (raise glucose)
ACE inhibitors (may enhance hypoglycaemia)
NSAIDs/salicylates (increase sulfonylurea effect)
rifampicin (reduce glimepiride effect)
azole antifungals and macrolides (may increase sulfonylurea levels)
iodinated contrast media (metformin—lactic acidosis risk)
cimetidine (increases metformin levels)

Always tell your doctor about all medicines you are taking, including over-the-counter drugs and supplements.

Pregnancy Safety

Not recommended; consult doctor (insulin preferred in pregnancy)

Alcohol Interaction

Avoid

Habit Forming

Storage

Store below 25°C in a dry place. Protect from moisture and direct light. Keep in original blister pack and out of reach of children.

Zoryl M D 2/1000 Tab — Safety Summary

Composition: Glimepiride (2mg) + Metformin (1000mg) + Dapagliflozin (10mg)
Prescription: Required (Rx)
Pregnancy: Not recommended; consult doctor (insulin preferred in pregnancy)
Alcohol: Avoid
Habit forming: No

Zoryl M D 2/1000 Tab — Safety FAQs

What should I do if I experience side effects?

Mild side effects often resolve on their own. If side effects are severe or persistent, stop the medicine and consult your doctor immediately.

Are all listed side effects common?

No. Some side effects are common while others are rare. Not everyone experiences side effects. Consult your doctor if you are concerned.

Can I take this medicine with other drugs?

Some medicines interact with each other. Always inform your doctor about all medicines you are currently taking.

When should I seek emergency help?

Seek immediate medical attention if you experience severe allergic reactions (difficulty breathing, swelling of face/throat), chest pain, or any life-threatening symptoms.

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Safety disclaimer

This information is for educational purposes only and is not a substitute for professional medical advice. If you experience severe side effects, seek medical attention immediately.