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Prescription requiredIntas Pharmaceuticals LtdAntidiabetic
Zoryl M D 2/1000 Tablet
Glimepiride (2mg) + Metformin (1000mg) + Dapagliflozin (10mg)
₹157MRP ₹1655% offIn stock
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Zoryl M D 2/1000 Tablet is used for type 2 diabetes mellitus in adults, to improve blood glucose control along with diet and exercise when single therapy is inadequate.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Licensed pharmacyPharmacist-verified orderDelivered across India
Key details
Salt: Glimepiride (2mg) + Metformin (1000mg) + Dapagliflozin (10mg)
Available variants: tablet 2mg + 1000mg + 10mg 10`S
Best price: ₹157 (₹15.68 per tablet)
MRP: ₹165
Prescription: Required
Manufacturer: INTAS PHARMACEUTICALS`
Ordering notes
Standard delivery across India. No same-day delivery nationally.
Chennai express delivery is possible and chargeable. Learn more
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy
Same salt, lower price
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Zoryl M D 2/1000 Tablet
tablet - 2mg + 1000mg + 10mg - 10 S
₹157
₹15.68 per tablet
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Same salt, different brand — what does that mean?
A substitute contains the same active ingredient (salt), in the same strength, as Zoryl M D 2/1000 Tablet. The medicine inside is the same — the brand name, manufacturer and price are what differ.
All medicines sold in India, branded or generic, must meet the quality standards set by the national drug regulator (CDSCO). A lower price does not mean lower quality.
Please confirm with your doctor or pharmacist before switching brands — they will check that the strength and form match your prescription.
Composition of Zoryl M D 2/1000 Tablet
Zoryl M D 2/1000 Tablet contains Glimepiride (2mg) + Metformin (1000mg) + Dapagliflozin (10mg). It belongs to the Sulfonylurea + Biguanide (combination) class of medicines.
Uses of Zoryl M D 2/1000 Tablet
- Type 2 diabetes mellitus in adults
- to improve blood glucose control along with diet and exercise when single therapy is inadequate
Key benefits
- Lowers fasting and post-meal blood sugar
- Improves insulin sensitivity
- Reduces liver glucose output
- Convenient combination therapy
- Helps improve HbA1c control
How Zoryl M D 2/1000 Tablet works
Glimepiride (a sulfonylurea) increases insulin release from pancreatic beta cells and improves insulin sensitivity. Metformin (a biguanide) reduces hepatic glucose production and improves peripheral glucose uptake, lowering insulin resistance.
How to take Zoryl M D 2/1000 Tablet
Oral tablet. Take exactly as prescribed, usually once daily with the first main meal (to reduce stomach upset and risk of low sugar). Swallow whole; do not crush/chew if SR/ER. Monitor blood glucose regularly.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
Missed dose and overdose
If you miss a dose
Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.
If you take too much
An overdose of this medicine can cause severe and prolonged low blood sugar, which may lead to fits or unconsciousness. It can cause a dangerous build-up of acid in the blood, with vomiting, severe weakness and laboured breathing. It can cause dehydration and a fall in blood pressure. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Side effects of Zoryl M D 2/1000 Tablet
Most side effects of Zoryl M D 2/1000 are mild and settle as the body adjusts. Reported side effects include:
- Hypoglycaemia
- nausea
- vomiting
- diarrhoea
- abdominal pain
- loss of appetite
- metallic taste
- dizziness
- headache
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
Safety advice for Zoryl M D 2/1000 Tablet
| Pregnancy | Not recommended; consult doctor (insulin preferred in pregnancy) |
|---|---|
| Breastfeeding | Not recommended while breastfeeding. |
| Alcohol | Avoid |
| Driving | May cause drowsiness or affect your concentration. Do not drive until you know how it affects you. |
| Kidney | Consult your doctor if you have kidney disease. |
| Liver | Consult your doctor if you have liver disease. |
| Habit forming | No |
Warnings and precautions
Risk of hypoglycaemia (especially with missed meals, alcohol, heavy exercise, elderly); carry glucose. Metformin can rarely cause lactic acidosis—risk increases with severe kidney disease, dehydration, sepsis, hypoxia, heart failure, liver disease, or excess alcohol; stop and seek care if rapid breathing, severe weakness, abdominal pain occur. Assess renal function before and during therapy; avoid if eGFR very low as per doctor. Temporarily stop metformin around iodinated contrast procedures or major surgery as advised. Use caution in G6PD deficiency (hemolysis risk with sulfonylureas).
Do not take Zoryl M D 2/1000 if
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for type 1 diabetes or for diabetic ketoacidosis. Not for people with severe kidney or liver disease. Not for people with severe kidney disease, severe liver disease, or an acute illness causing dehydration. Not for people who have had diabetic ketoacidosis. Not for people with severe kidney disease.
Interactions with other medicines
Alcohol (increases hypoglycaemia and lactic acidosis risk), insulin/other antidiabetics (additive hypoglycaemia), beta-blockers (mask hypoglycaemia), corticosteroids/thiazide diuretics/thyroid hormones (raise glucose), ACE inhibitors (may enhance hypoglycaemia), NSAIDs/salicylates (increase sulfonylurea effect), rifampicin (reduce glimepiride effect), azole antifungals and macrolides (may increase sulfonylurea levels), iodinated contrast media (metformin—lactic acidosis risk), cimetidine (increases metformin levels)
How to store Zoryl M D 2/1000 Tablet
Store below 25°C in a dry place. Protect from moisture and direct light. Keep in original blister pack and out of reach of children.
Expert advice for Zoryl M D 2/1000 Tablet
Take it shortly before a meal, and eat that meal. Check your sugar as often as your doctor has asked, especially when your routine changes. Take it with or just after food to reduce stomach upset. Keep taking it even when your sugar readings look normal — that is the medicine working. Continue your diet and physical activity; this medicine works alongside them, not instead of them. Take it in the morning so the extra urine does not disturb your sleep. Keep up your fluid intake and maintain genital hygiene. Tell any doctor treating you for an acute illness that you take this medicine.
Manufacturer and class
- Manufacturer:
- INTAS PHARMACEUTICALS`
- Therapeutic class:
- Antidiabetic
- Drug class:
- Sulfonylurea + Biguanide (combination)
Substitutes for Zoryl M D 2/1000 Tablet
Medicines with the same active ingredient (Glimepiride (2mg) + Metformin (1000mg) + Dapagliflozin (10mg)). Ask your doctor or pharmacist before switching brands.
| Medicine | Pack | Price | vs Zoryl M D 2/1000 Tablet |
|---|---|---|---|
| Isryl-Trio 2 mg TabletSYSTOPIC LAB | tablet · 10`S | ₹97 | 38% cheaper |
| Diapride Dm2 TabletMICRO LABS | tablet · 10`S | ₹133 | 15% cheaper |
| Sugaflo gm 2 Forte TabletLLOYD HEALTHCARE | tablet · 15`S | ₹176 | 12% more |
| Zoryl M 1 TabletIntas Pharmaceuticals Ltd | tablet · 20 Tablet | ₹221 | 41% more |
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Zoryl M D 2/1000 Tablet FAQs
What is Zoryl M D 2/1000 Tablet used for?
Zoryl M D 2/1000 Tablet is commonly used for Type 2 diabetes mellitus in adults, to improve blood glucose control along with diet and exercise when single therapy is inadequate. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Zoryl M D 2/1000 Tablet?
Zoryl M D 2/1000 Tablet contains Glimepiride (2mg) + Metformin (1000mg) + Dapagliflozin (10mg). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Zoryl M D 2/1000 Tablet?
Oral tablet. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Zoryl M D 2/1000 Tablet work?
Glimepiride (a sulfonylurea) increases insulin release from pancreatic beta cells and improves insulin sensitivity.
Is Zoryl M D 2/1000 Tablet a prescription medicine?
Yes. Zoryl M D 2/1000 Tablet is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Zoryl M D 2/1000 Tablet?
The side effects reported most often with Zoryl M D 2/1000 are Hypoglycaemia, nausea, vomiting, diarrhoea, abdominal pain. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Zoryl M D 2/1000 Tablet be taken during pregnancy?
Not recommended; consult doctor (insulin preferred in pregnancy) Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Zoryl M D 2/1000.
Can I drink alcohol while taking Zoryl M D 2/1000 Tablet?
Avoid
What if I miss a dose of Zoryl M D 2/1000 Tablet?
Take it as soon as you remember.
Is Zoryl M D 2/1000 Tablet habit forming?
No. Zoryl M D 2/1000 Tablet is not known to be habit forming when taken as prescribed.
Is there a cheaper substitute for Zoryl M D 2/1000 Tablet?
Isryl-Trio 2 mg Tablet has the same active ingredient and strength and is listed from ₹97 on PingMeDoc Pharmacy. Ask your doctor or pharmacist before switching brands, the salt is the same, but excipients and release profiles can differ.
How much does Zoryl M D 2/1000 Tablet cost on PingMeDoc Pharmacy?
Zoryl M D 2/1000 Tablet starts at ₹157 (MRP ₹165) on PingMeDoc Pharmacy. Available in tablet 2mg + 1000mg + 10mg 10`S. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Zoryl M D 2/1000 Tablet?
Zoryl M D 2/1000 Tablet is manufactured by INTAS PHARMACEUTICALS`. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Zoryl M D 2/1000 Tablet delivered?
Zoryl M D 2/1000 Tablet is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.
Zoryl M D 2/1000 Tablet, Quick facts
- Salt
- Glimepiride (2mg) + Metformin (1000mg) + Dapagliflozin (10mg)
- Form
- tablet
- Best price
- ₹157 (₹15.68 per tablet)
- MRP
- ₹165
- Prescription
- Required (Rx)
- Schedule
- Schedule H
- Brand
- Intas Pharmaceuticals Ltd
- Manufacturer
- INTAS PHARMACEUTICALS`
- Therapeutic class
- Antidiabetic
- Drug class
- Sulfonylurea + Biguanide (combination)
- Habit forming
- No
- Variants
- tablet 2mg + 1000mg + 10mg 10`S
- Delivery
- Standard across India
References
Compiled from the manufacturer's prescribing information and the sources below, and reviewed by a registered medical practitioner. It does not replace your own doctor's advice.
- Manufacturer labeling/pack insert, established medical literature (pharmacology texts)
- Indian prescribing information norms, standard clinical guidelines for diabetes
- Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
- National List of Essential Medicines (NLEM) 2022, Government of India.
- Manufacturer's package insert / prescribing information for Zoryl M D 2/1000 Tablet.
- World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.
Next steps
Safety disclaimer
Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.