Prescription requiredAntidiabetic

ZORYL-MD 1/500MG TAB — Side Effects & Warnings

Known side effects of ZORYL-MD 1/500MG TAB include Hypoglycaemia (low blood sugar), nausea, vomiting, diarrhoea, abdominal discomfort, loss of appetite, headache, dizziness, weight gain, metallic taste. Not everyone experiences these side effects.

Common Side Effects

Hypoglycaemia (low blood sugar)
nausea
vomiting
diarrhoea
abdominal discomfort
loss of appetite
headache
dizziness
weight gain
metallic taste

This is not an exhaustive list. Consult your doctor if you notice any unusual symptoms.

Important Warnings

Risk of hypoglycaemia (higher with missed meals, excess exercise, alcohol, or other antidiabetics); monitor blood glucose regularly. Metformin may rarely cause lactic acidosis—seek urgent care for rapid breathing, severe weakness, unusual muscle pain, abdominal pain, or drowsiness; risk increases with kidney/liver disease, dehydration, severe infection, heart failure, or heavy alcohol use. Use with caution/avoid in significant renal impairment; kidney function should be checked before and during therapy. Withhold metformin temporarily around iodinated contrast studies and major surgery as advised by a doctor. Not for type 1 diabetes or diabetic ketoacidosis.

Drug Interactions

ZORYL-MD 1/500MG TAB may interact with the following:

Alcohol
insulin and other antidiabetics (risk of hypoglycaemia)
beta-blockers (may mask hypoglycaemia)
ACE inhibitors (may enhance glucose-lowering)
corticosteroids and thiazide diuretics (may raise glucose)
rifampicin (may reduce effect)
fluconazole and other CYP2C9 inhibitors (may increase glimepiride effect)
iodinated contrast media (lactic acidosis risk)
cimetidine (may increase metformin levels)

Always tell your doctor about all medicines you are taking, including over-the-counter drugs and supplements.

Pregnancy Safety

Not recommended; consult doctor (insulin is generally preferred in pregnancy).

Alcohol Interaction

Avoid (increases risk of hypoglycaemia and metformin-associated lactic acidosis).

Habit Forming

Storage

Store below 25°C in a dry place, protected from light and moisture. Keep out of reach of children.

ZORYL-MD 1/500MG TAB — Safety Summary

Composition: Glimepiride 1 mg + Metformin 500 mg (as Metformin hydrochloride)
Prescription: Required (Rx)
Pregnancy: Not recommended; consult doctor (insulin is generally preferred in pregnancy).
Alcohol: Avoid (increases risk of hypoglycaemia and metformin-associated lactic acidosis).
Habit forming: No

ZORYL-MD 1/500MG TAB — Safety FAQs

What should I do if I experience side effects?

Mild side effects often resolve on their own. If side effects are severe or persistent, stop the medicine and consult your doctor immediately.

Are all listed side effects common?

No. Some side effects are common while others are rare. Not everyone experiences side effects. Consult your doctor if you are concerned.

Can I take this medicine with other drugs?

Some medicines interact with each other. Always inform your doctor about all medicines you are currently taking.

When should I seek emergency help?

Seek immediate medical attention if you experience severe allergic reactions (difficulty breathing, swelling of face/throat), chest pain, or any life-threatening symptoms.

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Safety disclaimer

This information is for educational purposes only and is not a substitute for professional medical advice. If you experience severe side effects, seek medical attention immediately.