Zoryl Mf 1

Glimepiride (a sulfonylurea) increases insulin release from the pancreas and improves insulin sensitivity. Metformin reduces glucose production by the liver and decreases intestinal glucose absorption while improving peripheral glucose uptake. Together they lower blood glucose more effectively than either alone.

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine can cause severe and prolonged low blood sugar, which may lead to fits or unconsciousness. It can cause a dangerous build-up of acid in the blood, with vomiting, severe weakness and laboured breathing. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Insulin/other antidiabetics (increased hypoglycaemia), alcohol (increased hypoglycaemia and lactic acidosis risk), iodinated contrast media (lactic acidosis risk), ACE inhibitors (may enhance glucose-lowering), corticosteroids/thiazide diuretics/sympathomimetics (may raise glucose), beta-blockers (may mask hypoglycaemia symptoms), fluoroquinolones (glucose disturbances), azole antifungals and macrolides (may increase sulfonylurea effect), rifampicin (may reduce sulfonylurea effect), cimetidine (may increase metformin levels)

Store below 25°C in a dry place, protected from light and moisture. Keep in original blister pack and out of reach of children.

<div class="style__desktop-container___1hcBT"><div class="style__desktop-video___2GTR9"><div class="styles__video-img___1rCzR"><div class=""/><div class=""/></div></div><div><div><div><div><div class="ExpertAdviceItem__content___1Djk2"><ul><li><div>You have been prescribed this combination medicine as it can control blood sugar better than metformin alone.</div></li> <li>You should continue to exercise regularly, eat a healthy diet, and take your other diabetes medicines along with Zoryl MF 1 Tablet.</li> <li>Take it with food to lower your chance of having an upset stomach.</li> <li>Monitor your blood sugar level regularly while you are taking this medicine. </li> <li>Inform your doctor about your diabetes treatment if you are due to have surgery under a general anesthetic.</li> <li>It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal. </li> <li>Tell your doctor immediately if you experience any deep or rapid breathing or if you have persistent nausea, vomiting, and stomach pain as Zoryl MF 1 Tablet may cause a rare but serious condition called lactic acidosis, which is an excess of lactic acid in the blood.</li> <li>Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).</li></ul></div></div></div></div></div></div>

Manufacturer:

Intas Pharmaceuticals Ltd

Marketed by:

INTAS PHARMACEUTICALS`

Therapeutic class:

diabetes

Drug class:

Sulfonylurea + Biguanide (Metformin) combination