Prescription requiredAntidiabetic

ZORYL MF 1 — Side Effects & Warnings

Known side effects of ZORYL MF 1 include Hypoglycaemia (low blood sugar), nausea, diarrhoea, abdominal pain, flatulence, metallic taste, headache, dizziness, weight gain, skin rash. Not everyone experiences these side effects.

Common Side Effects

Hypoglycaemia (low blood sugar)
nausea
diarrhoea
abdominal pain
flatulence
metallic taste
headache
dizziness
weight gain
skin rash

This is not an exhaustive list. Consult your doctor if you notice any unusual symptoms.

Important Warnings

Risk of hypoglycaemia (especially if meals are skipped, excessive exercise, alcohol use, or with other antidiabetics); carry glucose. Metformin may rarely cause lactic acidosis—risk increases with kidney impairment, dehydration, severe infection, heart/respiratory failure, liver disease, and heavy alcohol use. Check renal function before starting and periodically; avoid/use with caution in moderate renal impairment and do not use in severe renal impairment as advised by doctor. Temporarily stop metformin around iodinated contrast imaging and major surgery as directed. Use caution in elderly and in patients with G6PD deficiency (risk of haemolysis with sulfonylureas).

Drug Interactions

ZORYL MF 1 may interact with the following:

Insulin/other antidiabetics (increased hypoglycaemia)
alcohol (increased hypoglycaemia and lactic acidosis risk)
iodinated contrast media (lactic acidosis risk)
ACE inhibitors (may enhance glucose-lowering)
corticosteroids/thiazide diuretics/sympathomimetics (may raise glucose)
beta-blockers (may mask hypoglycaemia symptoms)
fluoroquinolones (glucose disturbances)
azole antifungals and macrolides (may increase sulfonylurea effect)
rifampicin (may reduce sulfonylurea effect)
cimetidine (may increase metformin levels)

Always tell your doctor about all medicines you are taking, including over-the-counter drugs and supplements.

Pregnancy Safety

Not recommended / Consult doctor (insulin is preferred in pregnancy); use only if clearly advised by physician.

Alcohol Interaction

Avoid (increases risk of hypoglycaemia and metformin-associated lactic acidosis).

Habit Forming

Storage

Store below 25°C in a dry place, protected from light and moisture. Keep in original blister pack and out of reach of children.

ZORYL MF 1 — Safety Summary

Composition: Glimepiride 1 mg + Metformin Hydrochloride 500 mg (modified release/sustained release)
Prescription: Required (Rx)
Pregnancy: Not recommended / Consult doctor (insulin is preferred in pregnancy); use only if clearly advised by physician.
Alcohol: Avoid (increases risk of hypoglycaemia and metformin-associated lactic acidosis).
Habit forming: No

ZORYL MF 1 — Safety FAQs

What should I do if I experience side effects?

Mild side effects often resolve on their own. If side effects are severe or persistent, stop the medicine and consult your doctor immediately.

Are all listed side effects common?

No. Some side effects are common while others are rare. Not everyone experiences side effects. Consult your doctor if you are concerned.

Can I take this medicine with other drugs?

Some medicines interact with each other. Always inform your doctor about all medicines you are currently taking.

When should I seek emergency help?

Seek immediate medical attention if you experience severe allergic reactions (difficulty breathing, swelling of face/throat), chest pain, or any life-threatening symptoms.

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Safety disclaimer

This information is for educational purposes only and is not a substitute for professional medical advice. If you experience severe side effects, seek medical attention immediately.