Acrotac 25MG Cap

Capsule

Treatment of severe psoriasis (including erythrodermic or pustular psoriasis) and other severe disorders of keratinisation when unresponsive to other therapies.

Acitretin is an oral retinoid that normalizes epidermal cell growth and differentiation. It reduces excessive keratinocyte proliferation and inflammation, improving scaling, thickening and plaque formation.

Take by mouth as prescribed, usually once daily with the main meal (fat-containing food improves absorption). Swallow capsule whole; do not crush or chew. Dose and duration are individualized; follow dermatologist’s advice and attend regular monitoring.

Dry lips, dry skin, peeling, itching, dry eyes, nosebleeds, hair thinning, headache, increased liver enzymes, increased triglycerides/cholesterol, photosensitivity

Highly teratogenic: contraindicated in pregnancy. Effective contraception is required for women of childbearing potential during treatment and for at least 3 years after stopping; regular pregnancy tests as advised. Do not donate blood during treatment and for 3 years after stopping. Avoid alcohol during treatment and for 2 months after stopping (can increase formation of etretinate and prolong teratogenic risk). Monitor liver function tests and lipid profile; use caution in liver disease, hyperlipidemia, diabetes, obesity. May cause mood changes, pseudotumor cerebri (severe headache/visual changes) and decreased night vision—avoid driving if affected. Avoid excessive sun/UV exposure.

Tetracyclines (risk of intracranial hypertension), vitamin A or other retinoids (additive toxicity), methotrexate (increased hepatotoxicity risk), alcohol (increases etretinate formation), phenytoin (protein binding interactions), progestin-only “minipill” contraception may be less reliable—use effective contraception as advised.

Store below 25°C in a cool, dry place, protected from light and moisture. Keep out of reach of children.

Acitret 25 Capsule, Neotigason 25 mg Capsule, Acretin 25 Capsule, Aceteret 25 Capsule, Acitretin 25 mg Capsule (generic)