Ampanel 2 Tablet

Drug | Tablet

Treatment of epilepsy: adjunct therapy for partial-onset (focal) seizures with or without secondary generalization, and primary generalized tonic-clonic seizures (as prescribed by neurologist)

Perampanel is an antiepileptic that selectively blocks AMPA-type glutamate receptors in the brain. This reduces excessive excitatory neurotransmission and helps prevent the abnormal electrical activity that triggers seizures.

Take exactly as prescribed, usually once daily at bedtime; may be taken with or without food. Swallow tablet whole with water. Do not stop abruptly; dose is usually titrated gradually. If a dose is missed, take the next dose at the usual time (do not double).

Dizziness, drowsiness, fatigue, headache, nausea, irritability, aggression, mood changes, imbalance/ataxia, falls, weight gain

May cause dizziness, sleepiness and impaired coordination—avoid driving/operating machinery until effects are known. Risk of serious psychiatric/behavioral reactions (aggression, anger, hostility, suicidal thoughts); seek medical help if mood/behavior changes occur. Use caution in elderly and those at risk of falls. Do not stop suddenly due to risk of increased seizures. Use caution in hepatic impairment; dose adjustment may be required.

Enzyme-inducing antiepileptics (carbamazepine, phenytoin, oxcarbazepine) may reduce perampanel levels; valproate and levetiracetam generally have minimal effect. Alcohol and other CNS depressants increase sedation and dizziness. May reduce efficacy of hormonal contraceptives at higher doses—use additional contraception as advised.

Store at room temperature (below 25°C), in original pack, protected from moisture and light. Keep out of reach of children.

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