Prevention (prophylaxis) of angina pectoris (chest pain) due to coronary artery disease; may be used as adjunct in chronic stable angina as per physician advice
How It Works
Glyceryl trinitrate is converted to nitric oxide in vascular smooth muscle, increasing cGMP and causing vasodilation. This reduces venous return (preload) and myocardial oxygen demand and also dilates coronary arteries to improve blood flow.
Frequently Asked Questions
What is this medicine used for?
Prevention (prophylaxis) of angina pectoris (chest pain) due to coronary artery disease; may be used as adjunct in chronic stable angina as per physician advice
Glyceryl trinitrate is converted to nitric oxide in vascular smooth muscle, increasing cGMP and causing vasodilation. This reduces venous return (preload) and myocardial oxygen demand and also dilates coronary arteries to improve blood flow.
How should I use this medicine?
Take as prescribed by the doctor, usually swallowed whole with water. Do not crush or chew the sustained-release capsule. It may be taken with or without food; try to take it at the same time each day. If a dose is missed, take it when remembered unless it is close to the next dose.
How should I store this medicine?
Store below 25°C in a cool, dry place, protected from light and moisture. Keep in original blister/strip and out of reach of children.
Do I need a prescription for this product?
Disclaimer
Product information is for awareness only and does not replace medical advice. Do not self-medicate for serious symptoms. For Rx medicines, a valid prescription is required. Consult your doctor or pharmacist for personalized guidance.
Sources: Manufacturer labeling/package insert, established medical literature (BNF/WHO/standard pharmacology texts), Indian drug information resources
Availability depends on stock and serviceability.
Directions for Use
Take as prescribed by the doctor, usually swallowed whole with water. Do not crush or chew the sustained-release capsule. It may be taken with or without food; try to take it at the same time each day. If a dose is missed, take it when remembered unless it is close to the next dose.
May cause marked hypotension and dizziness—rise slowly and avoid driving if symptomatic. Do not use with medicines for erectile dysfunction (PDE5 inhibitors) due to life-threatening fall in blood pressure. Use with caution in low blood pressure, dehydration, severe anemia, increased intracranial pressure, recent heart attack, hypertrophic obstructive cardiomyopathy, or severe aortic stenosis. Continuous use can lead to tolerance; follow the dosing schedule advised by the doctor.
Drug Interactions
PDE5 inhibitors (sildenafil, tadalafil, vardenafil), riociguat, other antihypertensives, alcohol, other nitrates, ergot derivatives (reduced effect), tricyclic antidepressants/antipsychotics (additive hypotension)
Storage Instructions
Store below 25°C in a cool, dry place, protected from light and moisture. Keep in original blister/strip and out of reach of children.
