Cloba-5 15S

Cloba-5 15S contains Clobazam 5 mg and is used for adjunct. Prescription required.

Adjunct treatment of epilepsy/seizure disorders (including Lennox–Gastaut syndrome); short-term management of severe anxiety (as prescribed).

Clobazam is a benzodiazepine that enhances the effect of the inhibitory neurotransmitter GABA at GABA-A receptors. This reduces abnormal electrical activity in the brain, helping control seizures and producing anxiolytic and sedative effects.

Tablet; take exactly as prescribed by the doctor. Can be taken with or without food, preferably at the same time each day. Do not stop suddenly; dose should be tapered to avoid withdrawal and rebound seizures.

Drowsiness, dizziness, fatigue, sleepiness, poor coordination (ataxia), slurred speech, confusion, memory impairment, nausea, constipation

May cause sedation, dizziness and impaired coordination—avoid driving/operating machinery. Risk of dependence and withdrawal with prolonged use; do not discontinue abruptly. Use with caution in elderly, liver/kidney impairment, history of substance use disorder, depression/suicidal thoughts, and respiratory disease (e.g., COPD, sleep apnea). Concomitant use with opioids, alcohol or other CNS depressants can cause profound sedation, respiratory depression, coma or death. Seek urgent help for allergic reactions or severe skin reactions (rare).

Alcohol and other CNS depressants (opioids, antihistamines, antipsychotics, sedatives) increase sedation/respiratory depression; valproate may increase clobazam active metabolite levels; carbamazepine/phenytoin/phenobarbital may alter clobazam levels; CYP2C19 inhibitors (e.g., omeprazole, fluconazole, fluvoxamine) can increase effects; CYP3A4 inducers (e.g., rifampicin) may reduce effect.

Store below 25°C in a dry place, protected from light and moisture. Keep out of reach of children.

Frisium 5 Tablet, Clobazam 5 mg Tablet (generic), Clobam 5 Tablet, Clobazam 5 Tablet (various brands)