DEBEGLAZID M60 TAB

Distributor inventory | Tablet

Type 2 diabetes mellitus (non-insulin-dependent), as an adjunct to diet and exercise to improve glycaemic control

Gliclazide is a sulfonylurea antidiabetic that stimulates insulin release from pancreatic beta cells by closing ATP-sensitive potassium channels. The modified-release formulation provides prolonged glucose-lowering effect over 24 hours, helping control fasting and post-meal blood sugar.

Oral tablet (modified-release). Take once daily with breakfast or the first main meal; swallow whole with water and do not crush/chew/split unless advised. Dose is individualized by the doctor; if a dose is missed, take the next dose at the usual time (do not double).

Hypoglycaemia, dizziness, headache, nausea, abdominal pain, diarrhoea, constipation, weight gain, skin rash/itching, increased liver enzymes

Risk of hypoglycaemia—more likely with missed meals, excess exercise, alcohol intake, elderly patients, or when used with other antidiabetics. Use with caution in kidney or liver impairment; monitor blood glucose and HbA1c regularly. Inform doctor if you have G6PD deficiency (risk of haemolysis), adrenal/pituitary insufficiency, or if you develop fever/infection/trauma (dose adjustment may be needed). Stop and seek care for severe allergic reactions, jaundice, or persistent hypoglycaemia. Not for type 1 diabetes or diabetic ketoacidosis.

Other antidiabetics/insulin (increased hypoglycaemia risk), fluconazole (increases gliclazide effect), miconazole (avoid; severe hypoglycaemia), macrolide antibiotics, quinolones, sulfonamides, warfarin (may increase anticoagulant effect), beta-blockers (mask hypoglycaemia symptoms), corticosteroids and diuretics (reduce glucose control), ACE inhibitors (may enhance hypoglycaemia), alcohol (increases hypoglycaemia risk)

Store below 25°C in a dry place, protected from moisture and light. Keep out of reach of children.

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