Drug | Tablet

Type 2 diabetes mellitus, Control of post‑meal (postprandial) blood glucose in type 2 diabetes when diet and exercise alone are insufficient

Glimepiride increases insulin release from the pancreas and improves insulin sensitivity. Metformin reduces glucose production in the liver and improves peripheral glucose uptake. Voglibose delays intestinal carbohydrate absorption, reducing post‑meal glucose spikes.

Take exactly as prescribed. Usually taken once daily with/just before the first main meal; swallow tablet whole (do not crush/chew, especially for modified‑release metformin). Monitor blood glucose regularly and follow diet/exercise advice.

Nausea, diarrhea, abdominal pain, flatulence, headache, dizziness, hypoglycaemia, weight gain, metallic taste

Risk of hypoglycaemia (especially with missed meals, excess exercise, alcohol, or other antidiabetics). Metformin may rarely cause lactic acidosis—risk increased in kidney impairment, dehydration, severe infection, heart/liver failure, or excessive alcohol; stop and seek urgent care if severe weakness, fast breathing, abdominal pain, or unusual sleepiness occurs. Avoid in severe renal impairment; periodic kidney function monitoring required. Temporarily withhold metformin around iodinated contrast procedures and major surgery as advised by doctor. Use caution in elderly and in people with irregular eating habits.

Other antidiabetics/insulin (increased hypoglycaemia), alcohol (increases hypoglycaemia and lactic acidosis risk), corticosteroids and thiazide diuretics (may raise glucose), ACE inhibitors (may enhance glucose‑lowering), beta‑blockers (may mask hypoglycaemia symptoms), fluoroquinolones (dysglycaemia), cimetidine (may increase metformin levels), iodinated contrast media (risk of lactic acidosis—temporary discontinuation), rifampicin (may alter metformin effect)

Store below 25°C, protect from moisture and light, keep in original blister pack, keep out of reach of children.

Glycomet Trio 2 Tablet, Glimestar MV 2 Tablet, Zoryl MV 2 Tablet, Amaryl MV 2 Tablet, Gluconorm MV 2 Tablet