Glycomet Trio 1 Forte

Glimepiride 2 mg + Metformin hydrochloride (sustained release) 1000 mg + Voglibose 0.3 mg tablets

Type 2 diabetes mellitus in adults when diet and exercise alone or dual therapy is inadequate; helps control post-meal and fasting blood glucose

Metformin reduces glucose production in the liver and improves insulin sensitivity. Glimepiride increases insulin release from the pancreas. Voglibose slows carbohydrate absorption from the intestine by inhibiting alpha-glucosidase, reducing post-meal glucose spikes.

Oral tablet; take exactly as prescribed, usually once daily with/after the main meal (often dinner) to reduce stomach upset and hypoglycaemia risk. Swallow whole; do not crush or chew (SR component).

Hypoglycaemia, nausea, diarrhoea, abdominal pain, flatulence, bloating, metallic taste, headache, dizziness, weight gain

Risk of hypoglycaemia (higher with missed meals, alcohol, strenuous exercise, elderly); monitor blood glucose. Metformin may rarely cause lactic acidosis—risk increases with kidney impairment, dehydration, severe infection, alcohol use, heart/respiratory failure; assess renal function before and during therapy. Avoid in severe renal or hepatic impairment; use caution in heart failure. Temporarily stop metformin before/after iodinated contrast or major surgery as advised by doctor. Seek help for symptoms of low sugar (sweating, tremor, confusion) or lactic acidosis (deep rapid breathing, severe weakness, abdominal pain).

Alcohol (increases hypoglycaemia/lactic acidosis risk), iodinated contrast media, insulin/other antidiabetics (additive hypoglycaemia), sulfonylureas/repaglinide (hypoglycaemia), beta-blockers (mask hypoglycaemia), corticosteroids/thyroid hormones/diuretics (raise glucose), ACE inhibitors (may increase hypoglycaemia), cimetidine and other OCT2/MATE inhibitors (increase metformin levels), NSAIDs and nephrotoxic drugs (worsen kidney function)

Store at room temperature (below 25°C), protected from moisture and light. Keep in original strip and out of reach of children.

Glycomet Trio 1, Glycomet Trio 2 Forte, Glimy M 2 Forte V, Glimepiride+Metformin SR+Voglibose 2/1000/0.3 tablets (generic), Glimibose M2 Forte