Reclimet OD 60 15S

Gliclazide (modified release) 60 mg

Treatment of type 2 diabetes mellitus to improve blood glucose control, as an adjunct to diet and exercise; may be used alone or with other antidiabetic medicines as prescribed.

Gliclazide is a sulfonylurea antidiabetic that stimulates insulin release from pancreatic beta cells and improves peripheral glucose utilization. The modified-release formulation provides sustained glucose-lowering over 24 hours.

Oral tablet (modified release). Take once daily preferably with breakfast, swallow whole with water; do not crush/chew/split unless advised. Dose is individualized by the doctor; take regularly and monitor blood glucose. If a dose is missed, take the next dose at the usual time (do not double).

Hypoglycaemia (low blood sugar), nausea, stomach upset, diarrhoea, constipation, headache, dizziness, weight gain, skin rash/itching, increased liver enzymes

Risk of hypoglycaemia—more likely with missed meals, excessive exercise, alcohol intake, elderly, kidney/liver impairment, or when used with other glucose-lowering drugs. Use with caution in renal/hepatic disease, malnutrition, adrenal/pituitary insufficiency, and G6PD deficiency (risk of haemolysis). Seek medical help for severe hypoglycaemia, jaundice, unusual bruising, or allergic reactions. Not for type 1 diabetes or diabetic ketoacidosis. Inform doctor before surgery/acute illness; dose adjustments may be needed.

Other antidiabetics (insulin, metformin, DPP-4 inhibitors, GLP-1 agonists) and alcohol increase hypoglycaemia risk; fluconazole, macrolide antibiotics, sulfonamides, quinolones, MAO inhibitors, beta-blockers (may mask hypoglycaemia), ACE inhibitors may enhance effect; corticosteroids, thiazide/loop diuretics, thyroid hormones, sympathomimetics may reduce glucose control; anticoagulants like warfarin (possible increased effect—monitor INR).

Store below 25°C, in original pack, protected from moisture and light. Keep out of reach of children.

Glyciphage MR 60 Tablet, Glycinorm-MR 60 Tablet, Diamicron MR 60 Tablet, Ziclaz MR 60 Tablet, Glizid MR 60 Tablet