Salazar DS Tablet

Salazar Ds Tablet contains Sulfasalazine (1000mg). Prescription required.

Ulcerative colitis (induction and maintenance of remission), Crohn’s disease (colonic involvement; as prescribed), Rheumatoid arthritis (disease-modifying treatment)

Sulfasalazine reaches the colon where gut bacteria split it into 5-aminosalicylic acid (5-ASA) and sulfapyridine. 5-ASA reduces intestinal inflammation, while sulfapyridine contributes to immunomodulatory/anti-inflammatory effects useful in rheumatoid arthritis.

Take as prescribed, usually after food with plenty of water. Swallow the delayed-release tablet whole; do not crush or chew. Maintain adequate hydration and follow the dosing schedule regularly.

Nausea, vomiting, abdominal pain, loss of appetite, headache, dizziness, rash, fever, orange/yellow discoloration of urine/skin, reversible low sperm count

Use with caution in patients with sulfonamide or salicylate allergy, G6PD deficiency, asthma, liver or kidney impairment, or blood disorders. May cause serious skin reactions, hepatitis, pancreatitis, and blood dyscrasias; seek care for rash, sore throat, fever, unusual bruising/bleeding, jaundice, or severe abdominal pain. Periodic CBC and liver function monitoring is recommended. May reduce folate levels—supplement if advised. Ensure good hydration to reduce risk of kidney stones.

Methotrexate (increased toxicity risk), warfarin/anticoagulants (bleeding risk/INR changes), azathioprine/6-mercaptopurine (myelosuppression risk), digoxin (reduced absorption), folic acid (reduced levels), antibiotics altering gut flora (may reduce effect), antidiabetic medicines (may increase hypoglycaemia risk)

Store below 25°C in a dry place, protected from light and moisture. Keep in original blister pack and out of reach of children.

Salazopyrin EN 1000 Tablet, Sulfasalazine 1 g Tablet (generic), Sazo 1000 Tablet, Sulfadin EN 1000 Tablet, Sulfazine EN 1000 Tablet